Hs-CRP, SAA and fasting lipids
| Healthy controls Median (range) | All patients with KD Median (range) | KD vs controls p Value (95% CI of diff) | KD CAA− Median (range) | CAA− vs controls p Value (95% CI of diff) | KD CAA+ Median (range) | CAA+ vs controls p Value (95% CI of diff) | p Value (Kruskal–Wallis)* | |
|---|---|---|---|---|---|---|---|---|
| Hs-CRP (mg/L) | 0.25 (0.00, 69.40) (n=49) | 0.47 (0.01, 84.98) (n=89) | p=0.25 (−0.05 to 0.29) | 0.46 (0.01, 11.16) (n=52) | p=0.30 (−0.07 to 0.28) | 0.60 (0.02, 84.98) (n=37) | p=0.35 (−0.08 to 0.44) | 0.51 |
| SAA (mg/L) | 0.80 (0.08, 14.71) (n=49) | 1.21 (0.07, 225.2) (n=89) | p=0.22 (−0.11 to 0.62) | 1.28 (0.07, 46.00) (n=52) | p=0.35 (−0.19 to 0.67) | 1.19 (0.13, 225.2) (n=37) | p=0.23 (−0.13 to 0.74) | 0.44 |
| Total cholesterol (mmol/L) | 4.40 (2.70, 5.90) (n=47) | 4.15 (2.50, 6.70) (n=84) | p=0.44 (−0.4 to 0.2) | 4.30 (2.50, 6.70) (n=49) | p=0.93 (−0.30 to 0.30) | 4.00 (2.60, 5.50) (n=35) | p=0.16 (−0.6 to 0.1) | 0.25 |
| LDL (mmol/L) | 2.27 (0.70, 4.34) (n=47) | 2.28 (0.93, 4.90) (n=84) | p=1.00 (−0.26 to 0.24) | 2.46 (1.04, 4.90) (n=48) | p=0.51 (−0.2 to 0.4) | 2.25 (0.93, 3.66) (n=35) | p=0.41 (−0.44 to 0.15) | 0.30 |
| HDL (mmol/L) | 1.40 (0.40, 2.40) (n=47) | 1.40 (0.70, 2.10) (n=83) | p=0.37 (−0.2 to 0.1) | 1.40 (0.70, 2.10) (n=48) | p=0.38 (−0.2 to 0.1) | 1.40 (0.90, 2.00) (n=35) | p=0.52 (−0.2 to 0.1) | 0.65 |
| TG (mmol/L) | 0.77 (0.39, 3.34) (n=47) | 0.81 (0.34, 2.66) (n=84) | p=0.74 (−0.09 to 0.14) | p=0.81 (0.43, 2.66) (n=49) | p=0.78 (−0.1 to 0.16) | p=0.81 (0.34, 1.57) (n=35) | p=0.77 (−0.12 to 0.16) | 0.94 |
All values are median (range) unless otherwise specified. Number (n) of subjects in each group as specified per test due to missing data points.
*p Values from Kruskal–Wallis test comparing three groups: controls, CAA− and CAA+. 95% CI of diff, 95% CI of the difference of median.
CAA, coronary artery aneurysms; HDL, high-density lipoprotein; hs-CRP, high-sensitivity C reactive protein; KD, Kawasaki disease; LDL, low-density lipoprotein; SAA, serum amyloid A; TG, triglycerides.