Change in pericardial effusion grade** in prespecified subgroups
| Subgroup | Placebo (n=99) N, mean±SD | Colchicine (n=98) N, mean±SD | Difference mean (95% CI) | p Value* |
|---|---|---|---|---|
| CRP level | ||||
| ≥30 mg/L (≥285.6 nmol/L) | (42) −1.3±1.4 | (40) −1.4±1.4 | −0.11 (−0.72 to 0.49) | 0.81 |
| <30 mg/L (<285.6 nmol/L) | (54) −1.0±1.2 | (56) −1.3±1.2 | −0.27 (−0.72 to 0.18) | 0.12 |
| VKA+other AC | ||||
| Yes | (50) −0.9±1.3 | (52) −1.4±1.2 | −0.48 (−0.99 to 0.02) | 0.06 |
| No | (49) −1.3±1.2 | (46) −1.2±1.3 | 0.11 (−0.40 to 0.63) | 0.81 |
*By non-parametrical Mann–Whitney test.
AC, anticoagulants; CRP, C reactive protein; VKA, vitamin K antagonist.
**Effusion grade (0 to 4) based on echo-free space width of<1 mm (1), 1–9 mm (2), 10–14 mm (3) or ≥15 mm (4).