Table 1

Baseline characteristics of patients above or below the respective cut-off levels for MR grade, LVEF and plasma BNP

	All patients (n=725)	MR >1/≤1 (n=90/635)	p Value	LVEF <0.40/≥0.40 (n=110/615)	p Value	BNP >373/≤373 (n=180/545)	p Value
Mean age (years)	65	70/64	<0.0001	70/64	<0.0001	70/63	<0.0001
Female (%)	29	39/28	0.05	24/30	0.17	37/27	0.01
History (%)
MI	20	36/18	0.0002	36/17	<0.0001	29/17	0.001
Angina pectoris	40	59/38	0.0002	43/40	0.60	47/38	0.04
CHF	8	27/5	<0.0001	22/5	<0.0001	17/5	<0.0001
PCI/CABG	12	21/11	0.02	16/12	0.21	15/12	0.24
Risk factors (%)
Current smoker	34	27/35	0.18	38/33	0.32	30/35	0.27
Diabetes mellitus	18	26/17	0.04	18/18	0.89	21/17	0.26
Hypertension	40	51/39	0.03	42/40	0.75	51/37	0.0008
Hypercholesterolaemia	28	31/28	0.53	32/27	0.36	24/29	0.22
GFR <60 ml/min	38	62/35	<0.0001	53/36	0.001	59/31	<0.0001
Diagnosis (%)
STEMI	47	43/48	0.43	49/47	0.76	46/48	0.73
Anterior	48	26/50	0.004	74/43	<0.0001	57/45	0.06
Inferior	50	64/49	0.09	19/56	<0.0001	39/54	0.02
Unspecified	2	10/<1	0.004	7/1	0.01	5/1	0.06
Non-STEMI	35	43/34	0.10	39/35	0.39	46/32	0.0006
Unstable angina pectoris	17	13/18	0.37	12/18	0.10	8/21	<0.0001
10-year mortality (%)	36.3	70.2/31.5	<0.0001	67.5/30.7	<0.0001	56.3/29.4	<0.0001

BNP, brain natriuretic peptide; CABG, coronary artery bypass grafting; CHF, congestive heart failure; GFR, glomerular filtration rate; LVEF, left ventricular ejection fraction; MI, myocardial infarction; MR, mitral regurgitation, PCI, percutaneous coronary intervention; STEMI, ST segment elevation myocardial infarction.