Multivariate time-dependent analysis of risk for death/cardiac transplantation (Cox proportional hazard model)
| Variable | HR (95% CI) | p Value | C-statistic |
| Raised BNP | 1.39 (0.78 to 2.48) | 0.258 | |
| Troponin T ≥0.01 ng/ml | 2.18 (1.25 to 3.80) | 0.006 | |
| NYHA class (IV vs III) | 3.28 (1.63 to 6.61) | <0.001 | |
| History of myocardial infarction | 1.36 (0.80 to 2.32) | 0.252 | |
| Biventricular pacemaker | 3.42 (1.52 to 7.68) | 0.003 | |
| Raised MR-proANP* | 4.56 (1.08 to 19.32) | 0.039 | 0.709 |
| Raised copeptin* | 1.86 (0.84 to 4.12) | 0.126 | 0.705 |
↵* Each biomarker added separately to the multivariate model. B=type natriuretic peptide; BNP, NYHA, New York Heart Association; CI, confidence interval; HR, hazard ratio; MR-proANP, midregional proatrial natriuretic peptide.