Preoperative and perioperative characteristics in patients with and without antiplatelet therapy
| Antiplatelet therapy | No antiplatelet therapy | p Value | |
|---|---|---|---|
| N | 43 | 90 | |
| Age (years) | 62±10 | 59±11 | 0.24 |
| Gender (% women) | 16 (37%) | 29 (32%) | 0.57 |
| Ejection fraction (%) | 54±9 | 55±10 | 0.85 |
| Heart rate (BPM) | 67±15 | 75±18 | 0.019 |
| Systolic blood pressure (mm Hg) | 127±28 | 127±35 | 0.98 |
| Diastolic blood pressure (mm Hg) | 69±15 | 71±24 | 0.73 |
| Preoperative haemoglobin (g/l) | 134±14 | 134±16 | 0.88 |
| Platelet count (×109/l) | 228±71 | 227±80 | 0.97 |
| Serum creatine (μmol/l) | 83±26 | 95±44 | 0.11 |
| Cardiac tamponade | 7 (16%) | 24 (27%) | 0.19 |
| Intramural haematoma | 7 (16%) | 15 (17%) | 0.96 |
| Operation time (min) | 429±149 | 404±148 | 0.36 |
| CBP time (min) | 208±57 | 194±61 | 0.24 |
| Aortic clamp time (min) | 89±37 | 87±35 | 0.73 |
| Circulatory arrest (min) | 27±12 | 25±11 | 0.56 |
| Intraoperative bleeding (ml) | 1800 (950–4250) | 800 (500–2500) | 0.010 |
| Postoperative bleeding (ml) | 800 (420–1605) | 500 (390–1070) | 0.037 |
| Transfusion RBC (units) | 14 (7.5–24) | 9 (3–17) | 0.066 |
| Transfusion plasma (units) | 12 (6–25) | 9 (3–19) | 0.17 |
| Transfusion platelets (units) | 5 (3–8) | 3 (2–7) | 0.08 |
| Transfusion total (units) | 32 (19–55) | 20 (8–42) | 0.10 |
| Massive bleeding | 6 (28%) | 21 (23%) | 0.21 |
Mean±SD, median (IQR) or number and %.
BPM, beats per minute; CBP, cardiopulmonary bypass; RBC, red blood cell.