Studies showing the relationship between reduction of uric acid and improvement in endothelial function
| Study population | Citation | Relative improvement |
|---|---|---|
| Congestive heart failure | Doehner et al69 | 58% improvement |
| Congestive heart failure | Farquharson et al70 | 50% improvement |
| Congestive heart failure | George et al71 | 30% improvement |
| Normotensive type 2 diabetes | Dogan et al118 | 50% improvement |
| Patients with obstructive sleep apnoea | El Solh et al117 | 30% improvement |
| Patients with metabolic syndrome | Yiginer et al119 | 50% improvement |
| Patients with type 2 diabetes | Butler et al114 | 30% improvement |
| Asymptomatic hyperuricaemia | Kanbay et al120 | 20% improvement |
| Asymptomatic hyperuricaemia | Mercuro et al116 | 30% improvement |
| Asymptomatic hyperuricaemia | Melendez-Ramirez et al121 | 40% improvement |
| Patients with chronic kidney disease | Yelken et al122 | 100% improvement |
| Patients with chronic kidney disease | Kao et al123 | 25% improvement |