Baseline characteristics of the first 100 patients
| Age—years (median; IQR) | 77; 18.5 |
| BMI (kg/m2) (median; IQR) | 23.8; 5.3 |
| Gender (male) (%) | 67 |
| Hypertension (%) | 66 |
| Hyperlipidaemia (%) | 44 |
| Diabetes (%) | 13 |
| Coronary artery disease (%) | 45 |
| Previous myocardial infarction (%) | 34 |
| Previous PCI (%) | 31 |
| Previous CABG (%) | 17 |
| Previous valve surgery (%) | 6 |
| Previous vascular surgery or of the thoracic aorta (%) | 3 |
| Previous episode of congestive heart failure (%) | 77 |
| NYHA class | |
| I/II | 18 |
| III | 62 |
| IV | 20 |
| Comorbidities | |
| COPD (%) | 20 |
| Previous cerebrovascular infarction (%) | 9 |
| Renal failure (%) | 50 |
| Cancer of any type (%) | 11 |
| Logistic EuroSCORE (%) (median; IQR) | 16.9; 19.1 |
| nt-proBNP (ng/l) (median; IQR) | 3202; 3621 |
| Chronic/intermittent atrial fibrillation (%) | 52 |
| Previous PM or ICD implantation (%) | 28 |
| CRT (%) | 13 |
| Mitral valve—grade of mitral regurgitation at baseline | |
| Moderate to severe | 30 |
| Severe | 70 |
| MR aetiology | |
| Functional/functional ischaemic | 62 |
| Degenerative | 38 |
| LVEF (mean; SD) | 0.48; 0.19 |
| LVEDV (ml) (mean; SD) | 158; 92 |
| LVESV (ml) (mean; SD) | 93; 84 |
| EDVI (ml/m2) (mean; SD) | 87; 48 |
| LA diameter (mm) (mean; SD) | 51; 11 |
| RV-RA gradient (mm Hg) (mean; SD) | 47; 15 |
BMI, body mass index; BNP, brain natriuretic protein; CABG, coronary artery bypass graft; COPD, chronic obstructive lung disease; CRT, cardiac resynchronisation therapy; EDVI, end-diastolic volume index; EuroSCORE, European System for Cardiac Operative Risk Evaluation; ICD, implantable cardioverter defibrillator; LA, left atrium; LVEDV, left ventricular end-diastolic volume; LVEF, left ventricular ejection fraction; LVESV, left ventricular end-systolic volume: PCI, percutaneous coronary intervention; PM, pacemaker; RA, right atrium; RV, right ventricle.