Risk of coronary heart disease (all CHD) associated with stress resilience, physical fitness and body mass
| Unadjusted | Adjusted | ||||
|---|---|---|---|---|---|
| Event rates/1000 person-years (95% CI) | Model 1 HR (95% CI) | Model 2 HR (95% CI) | Model 3 HR (95% CI) | Model 4 HR (95% CI) | |
| Main exposure | |||||
| Stress resilience | |||||
| 1. High (7–9) | 1.59 (1.52 to 1.67) | Reference | Reference | Reference | Reference |
| 2. Moderate (4–6) | 1.97 (1.92 to 2.03) | 1.24 (1.18 to 1.30) | 1.18 (1.12 to 1.25) | 1.09 (1.02 to 1.15) | 1.04 (0.98 to 1.09) |
| 3. Low (1–3) | 2.61 (2.52 to 2.70) | 1.65 (1.56 to 1.75) | 1.54 (1.45 to 1.63) | 1.28 (1.21 to 1.36) | 1.17 (1.10 to 1.25) |
| Mediators | |||||
| Physical fitness (per unit change, 0–9) | 0.93 (0.92 to 0.94) | 0.93 (0.92 to 0.94) | |||
| Body mass index (kg/m2) | |||||
| Underweight (<18.49) | 1.70 (1.60 to 1.80) | 0.88 (0.83 to 0.94) | 0.78 (0.73 to 0.83) | ||
| Normal weight (18.5–24.99) | 1.92 (1.80 to 1.96) | Reference | Reference | ||
| Overweight (25.0–29.99) | 3.36 (3.17 to 3.36) | 1.76 (1.66 to 1.88) | 1.63 (1.53 to 1.74) | ||
| Obese (≥30.0) | 5.22 (4.63 to 5.89) | 2.79 (2.47 to 3.15) | 2.23 (1.97 to 2.52) | ||
Model 1. Unadjusted.
Model 2. Adjusted for childhood factors (birth year, region, parental SEI and household crowding).
Model 3. Adjusted for 2+ characteristics in adolescence (cognitive function, diastolic and systolic blood pressure and CVD diagnosis at conscription).
Model 4. Adjusted for 2+3+ physical fitness and body mass index in adolescence.
CVD, cardiovascular disease; SEI, socioeconomic index.