Baseline clinical characteristics for the participants stratified according to major adverse cardiovascular (MACE) outcome
| All (n=1915) | No MACE (n=1532) | MACE (n=383) | p Value | |
|---|---|---|---|---|
| Age (years)* | 58±16 | 55±16 | 71±11 | <0.001 |
| Male gender | 42% | 41% | 49% | 0.006 |
| Systolic blood pressure (mm Hg)* | 136±23 | 133±22 | 148±21 | <0.001 |
| Diastolic blood pressure (mm Hg)* | 78±12 | 78±12 | 81±13 | <0.001 |
| Heart rate (bpm)* | 67±12 | 66±11 | 70±12 | <0.001 |
| Hypertension | 43% | 36% | 73% | <0.001 |
| Diabetes | 10% | 8% | 19% | <0.001 |
| Smoking status | ||||
| Never | 33% | 36% | 25% | |
| Previous | 33% | 31% | 42% | <0.001 |
| Current | 33% | 33% | 34% | |
| Cholesterol* | 5.5±1.2 | 5.5±1.2 | 5.6±1.1 | 0.247 |
| Previous ischaemic heart disease | 6% | 2% | 23% | <0.001 |
| Previous ischaemic stroke | 2% | 1% | 5% | <0.001 |
| BMI (kg/m2)* | 25.4±3.9 | 25.1±3.8 | 26.9±4.1 | <0.001 |
| eGFR (mL/min/1.73 m2)* | 76.3±16.2 | 77.2±15.5 | 72.4±18.0 | <0.001 |
| Atrial fibrillation/flutter | 2% | 1% | 6% | <0.001 |
*Mean±SD.
BMI, body mass index; eGFR, estimated glomerular filtration rate.