Table 2

Individual PAH patient characteristics, including medication.

Age (yrs)	Weight (kg)	BMI (kg/m²)	WHO Class	Medication*
Diagnosis†: IPAH
63	59	26.2	1	SIL, TREPIN, VAL, O2
31	70	28.4	1	AMB, SIL, TREPIN, DIG, O2
33	64	22.7	1	NIF, WAR
33	57	20	1	SIL, WAR, PPI
33	91	28,1	1	THY, PRE, TREPIV, O2, intravenous immunoglobuline, IRO, WAR, VEN, AMI, SPI, LIS, TOR, BOS, PPI, TRAM, PRC
49	59	21,7	1	BOS, FUR, NIF, WAR, SAL, SER
40	94	34,5	1	AMB, AML, FUR, TAD
26	58	19,4	1	AML, FUR, SIL, WAR
41	59	20.9	2	BOS, SIL, NIF, WAR
50	49	19.9	2	BOS, TAD, ASA, SIM, SER
47	70	28.4	2	BOS, TREPIV, HCT, WAR, ESC, GAB
19	54	21.9	2	SIL, TREPIV, FUR, ALD, DIG, WAR, IRO, PPI
74	84	29.8	2	SIL, THY, WAR, SD, CEL
50	102	36.1	2	BOS, SIL, FUR, ALD, WAR, FLU, FEX, PPI
60	75	31.2	2	AMB, TRI, ALD, NAP
44	61	23.8	2	EPIV, ALD, FLU, BUP, GAB
38	78	26.1	2	BOS, TAD, TREPIV, FUR
49	86	30.5	2	AMB, AML, TREPIN, TOR, HCT, PRA, PPI, O2
31	68	22.2	2	PGI, WAR, ESC, GAB, PPI
34	51	22.7	2	BOS, SIL, TREPSC, FUR, DIG, IRO, HYD, PRE
48	68	25	2	AMB, TAD, TREPPO, CAV, WAR, BUM, RIS, PPI, TRAM, HYD, Calcium, CET, TEM, TRA, ALP
43	88	35	2	BOS, SIL, SPI, FUR, ATO, WAR, ILO
68	53	19,5	2	NIF, WAR, SIM, FLU, PPI, ASA, ALP, IRO, PRC, COD, RAN
52	71	27,4	2	BOS, TAD, SPI, FUR, MEF, SIT, LIS, DIG, CLG, DUL, LOV, THY, KCL, FAM
37	109	33,6	2	TAD, AMB, WAR, CET, RAN, SER, GUA, FLT
48	66	24,8	2	TREPIN, BOS, DIG, TAD, DIL
21	61	23	2	SIL, AMB, WAR, DIG, PPI, FUR, SPI, Depo Provera
31	56	21,9	2	SIL, AMB, TREPPO, PPI, TOP, SOL, DIG
65	51	24,6	2	NIF, THY, SIL, VYT
60	66	24,8	2	TREP, AMB, TAD, GAB, DIG, SPI, SER
39	64	27,7	2	TREP, BOS, FUR, PPI, SPI
29	56	19,4	2	AMB, TAD, TOP, DAB, FUR, IRO
44	38	14	2	FSA, AMT, AZE, WAR, DIG, FUR, HCT, PPI, MTZ, CIC, O2, PRM, TREPIV, SIL, SPI, TRAM, TRC, LEV
69	75	28,2	2	AMB, DIL, CLO, LIS, MEF, PIO, FUR, RAN, ROS, SIT, AMT, REP, DAB, MET
45	52	20,3	2	TREPIN, BOS, FUR, WAR
32	88	34,4	2	PRC, BOS, Calcium, IMB, Immodium, LOR, O2, RAN, THY, TREPIV
65	84	27,4	2	DIL, RAL, RAN, FLT, BOS, SPI, Finacea, ASA, CLB, CIT, BME, TREPIN
44	54	19,8	3	SIL, AMB, IMB, EPIV, Calcium, THY, TOR, PPI, DIL, MON, CET, SPI
38	70	28,4	3	BOS, WAR, NOR, ARG, AML, HCT, SD, MOM
48	86	37,2	3	EPIV, BOS, TAD, FUR, PPI, IRO, FA
59	86	31.6	3	AMB, SIL, TREPIN, FUR, ALD, WAR, SIM, IRO, OM3, PPI
Diagnosis: CTD*
50	107	37.9	2	BOS, SIL, DIL, FUR, WAR, O2
62	64	26.3	2	SIL, MTX, PPI
77	72	27.1	2	BOS, NIF, HCT, THY, PRED, MTX, OM3
58	70	27.3	2	TAD, HCT, WAR, IRO
50	60	26.0	2	AMB, AML, FUR, ALD, DIG, ALL, COL, URS, O2
51	54	23.4	2	BOS, SIL, DIL, THY, PRED
52	104	38.2	2	BOS, SIL, TREPIN, FUR, BUM, THY, INS, DUL, PRE
57	84	30.9	2	NIF, TREPIV, MTX, PRED, FA, PPI
46	91	36,9	2	SIL, QUE, WAR, TREPIN, PPI, HXC, LOZ
60	68	22,7	2	TREPIN, AMB, SIL, FUR
57	52	20,3	2	AMB, FUR, BUP, CIT, PPI, PEN, ZOL, FEX
57	64	26,0	2	BOS, TAD, FUR, SPI, O2
40	82	26.8	3	BOS, SIL, AML, TREPIV, FUR, ALD, PRED, LOS, CLO, ATE
66	83	31.2	3	BOS, SIL, FUR, ALD, THY, LIS, PRED, AZA, PPI, PAR, O2
28	58	21,8	2	TREPIV, SIL, WAR, HXC, FUR, PRC/OXC, MMF, FLU, THY, PRED, FA, PPI, RAN, ZOL
50	63	25,2	4	PPI, DOM, SIL, AMB, FUR, AML, FA, PRE, LOR

*Medications (prostanoids are in bold): ALD=aldactone PO; ALL=allopurinol PO; AMB=ambrisentan PO; AML=amlodipine PO; ALP=alprazolam PO; AMI=amiloride PO; AMT=amitryptilin PO; ARG=l-arginine PO; ASA=acetylsalicylic acid; ATE=atenolol PO; ATO=atorvastatine PO; AZA=azathioprine PO; AZE=azelastine PO; BME=betamethasone PO; BOS=bosentan PO; BUM=bumetanide PO; BUP=bupropion PO; CAV=carvedilol PO; CET=cetirizine PO; CIC=ciclenosid PO; CIT=citalopram PO; CLB=clobetasol topical; CLG=clopidogrel PO; CLO=clonidine PO; COD=codein PO; COL=colchicin PO; DAB=dabigatranexilat PO; DIG=digoxin PO; DIL=diltiazem; DIP=dipyridamole; DOM=domperidone PO; DUL=duloxetine PO; EPIV=epoprostenol IV; ESC=escitalopram PO; FA=folic acid PO; FAM=famotidin PO; FEX=fexofenadine PO; FLT=fluticasone INH; FLU=fluoxetin PO; FSA=fluticasone/salmeterol INH; FUR=furosemide PO; GAB=gabapentin PO; GUA=guifenesin PO; HCT= hydrochlorothiazide PO; HXC=hydroxychloroquine PO; HYD=hydrocodone; ILO=iloprost INH; IMB=imatinib PO; INS=insulin; IRO=iron PO; LEV=levabuterol INH; LIS=lisinopril PO; LOR=loratadin PO; LOS=losartan PO; LOV=lovastatin PO; MED=medodrine; MEF=metformin PO; MET=metoprolol PO; MMF=mycophenolat- mofetil PO; MOM=mometasone PO; MON=montelukast inhal.; MTX=methotrexate PO; MTZ=metronidazole PO; NIF=nifedipine; NOR=norethindrone PO; O2=oxygen by nasal canula; OM3=omega-3-acid ethyl esters PO; OXC=ocycodon PO; PAR=paroxetine PO; PGI=prostanoid; PPI=proton pump inhibitor PO; PRA=pravastatin PO; PRC=paracetamolo PO; PRE=pregabalin; PRED=prednisone PO; PRM=promethazin PO; QUE= quetiapin PO; RAL=raloxifen PO; RAN=ranitidine PO; RIS=risedronate PO; SAL=salmeterol INH; SD=PH study drug; SER=sertraline PO; SIL=sildenafil PO; SIM=simvastatine PO; SIT=sitagliptin PO; SOL=solifenacinsuccinat PO; SPI=spironolactone PO; TAD=tadalafil PO; TEM=temazepam PO; THY=levothyroxine PO; TOP=topiramat PO; TOR=torsemide PO; TRA=trazodone; TRC=triamcinolon PO; TRAM=tramadole; TREP=trepostinil; TREPIV=trepostinil IV; TREPIN=trepostinil inhal.; TREPPO=trepostinil PO ; TREPSC=trepostinil subcutaneously; TRI=triamterene PO; URS=ursodiol PO; VAL=valsartan PO; VEN=venlaxafine PO; VYT=ezetimibe/simvastatin PO; WAR=warfarin PO; ZOL=zolpidem PO †Clinical Classification of Pulmonary Hypertension (World Symposium on PH; Nice 2013) as described in Simonneau G, J Am Coll Cardiol 2013. Parenteral prostacyclin administration (intravenous, inhaled, subcutaneous) in the far right column is indicated in bold letters. The definition of WHO functional class of PAH can be found in Rubin LJ. Diagnosis and management of pulmonary arterial hypertension: ACCP Evidence-Based Clinical Practice Guidelines. Introduction. Chest 2004;126:7S–10S. BMI, body mass index; CTD, PAH associated with connective tissue disease (WSPH Nice PH category 1.4.1); DTI, PAH drug and toxin induced (Nice PH category 1.3); HPAH, heritable PAH (Nice PH category 1.2.); IPAH, idiopathic PAH (Nice PH category 1.1); IV, intravenous; PAH, pulmonary arterial hypertension; PO, oral; SC, subcutaneous; SSRI, selective serotonin reuptake inhibitor.