Table 1

Patient characteristics by risk group

Risk group	Lowest risk	2	3	4	5	6	7	8	9	Highest risk	Overall
Patient average covariate profiles based on tenths of patient population grouped by 5-year risk of composite CVD event estimated at baseline
Number of patients in dataset	10 035	9903	9797	9626	9516	9455	9382	9335	9249	8668	94 966
5-year risk (%; average across patients)	3.69	5.70	7.37	9.15	11.20	13.71	17.14	22.14	30.42	52.37	16.68
5-year risk (%; at average covariate values)	3.46	5.43	6.95	8.53	10.36	12.57	15.64	20.07	27.23	44.18	11.64
Sociodemographic characteristics
Sex (% female)	64	48	42	39	37	37	38	42	44	46	44
Age (years if male)	49	55	59	62	65	67	71	74	77	81	67
Age (years if female)	53	62	67	70	73	75	78	80	83	87	72
Age (weighted average)	52	59	62	65	68	70	73	76	80	84	69
Most deprived quintile (%)	15	17	18	19	20	21	21	22	22	24	20
Stable-CAD diagnosis (%)
NSTEMI	0	1	3	5	8	10	12	17	23	43	10
STEMI	1	4	8	12	13	14	13	9	6	4	7
Unstable angina	10	13	12	12	12	12	13	15	17	15	14
Stable angina	78	65	56	49	43	39	37	34	29	18	47
Non-specific CHD	11	17	20	22	24	24	25	26	25	20	23
Stable-CAD severity (%)
PCI in past 6 months	9	12	13	14	13	13	11	9	6	4	9
CABG in past 6 months	9	7	6	5	5	4	4	3	2	1	4
Previous/recurrent MI	2	6	10	14	18	23	26	29	32	43	18
Use of nitrates	10	16	19	21	24	28	33	37	43	56	28
CVD risk factors
Smoking status (%)
Current smoker	31	35	36	37	38	38	37	35	32	30	35
Ex-smoker	27	30	31	32	32	33	34	34	34	34	32
Never smoked	41	35	33	31	30	29	29	31	33	36	33
Hypertension (%)	69	70	71	71	72	74	76	79	83	87	76
Diabetes (%)	4	8	10	12	14	16	18	21	24	32	16
Total cholesterol (mmol/L)	4.95	4.91	4.84	4.79	4.74	4.74	4.70	4.68	4.64	4.54	4.79
HDL (mmol/L)	1.41	1.37	1.35	1.35	1.35	1.35	1.36	1.37	1.37	1.35	1.37
CVD comorbidities (%)
Heart failure	5	7	9	12	15	19	27	37	52	73	26
Peripheral arterial disease	1	2	3	4	6	8	10	13	16	25	8
Atrial fibrillation	3	5	7	9	10	13	16	21	29	43	15
Stroke	0	1	1	2	3	5	8	14	22	39	9
Non-CVD comorbidities (%)
Chronic kidney disease	2	2	3	4	4	5	7	9	12	20	7
Chronic obstructive pulmonary disease	20	20	20	21	22	23	25	27	28	30	23
Cancer	4	5	6	7	8	9	11	13	14	12	9
Chronic liver disease	0	1	1	1	1	1	1	1	1	1	1
Psychosocial characteristics
Depression at diagnosis (%)	20	17	15	15	14	14	15	17	18	21	17
Anxiety at diagnosis (%)	7	6	6	7	7	7	8	8	10	12	8
Biomarkers
Heart rate (bpm)	72	71	71	71	71	71	72	73	74	76	72
Creatinine (mmol/L)	88	92	95	96	98	100	101	104	109	125	100
White cell count (10⁹/L)	6.81	7.05	7.19	7.31	7.44	7.54	7.62	7.76	7.88	8.22	7.46
Haemoglobin (g/100 mL)	1.43	1.43	1.42	1.41	1.39	1.37	1.35	1.32	1.28	1.22	1.36

Deprivation measured by index of multiple deprivation, 2010. All values in table are means. Percentage of missing data imputed: smoking status 32%, total cholesterol 54%, HDL 55%, heart rate 78%, creatinine 38%, white cell count 56% and haemoglobin 53%.
CABG, coronary artery bypass graft; CAD, coronary artery disease; CHD, coronary heart disease; CVD, cardiovascular disease; HDL, high-density lipoprotein; MI, myocardial infarction; NSTEMI, non-ST segment elevation myocardial infarction; PCI, percutaneous coronary intervention; stable-CAD, stable coronary artery disease; STEMI, ST segment elevation myocardial infarction.