Bivariate association of high-sensitivity cardiac troponin I with study covariates among controls (n=1135)
| Quartile I (n=287) | Quartile II (n=280) | Quartile III (n=286) | Quartile IV (n=282) | p Value | |
|---|---|---|---|---|---|
| Age, mean (SD) | 62.8 (6.8) | 62.5 (7.4) | 60.7 (8.7) | 62.5 (7.7) | 0.004 |
| Female, n (%) | 141 (49.1) | 138 (49.3) | 142 (49.7) | 137 (48.6) | 1.0 |
| Race/ethnicity, n (%) | |||||
| White | 186 (64.8) | 179 (63.9) | 177 (61.9) | 163 (57.8) | 0.01 |
| Black | 15 (5.2) | 18 (6.4) | 27 (9.4) | 41 (14.5) | |
| Hispanic/Latino | 32 (11.2) | 32 (11.4) | 26 (9.1) | 28 (9.9) | |
| Asian | 33 (11.5) | 27 (9.6) | 25 (8.7) | 18 (6.4) | |
| Other/mixed | 21 (7.3) | 24 (8.6) | 31 (10.8) | 32 (11.4) | |
| Education level, n (%) | |||||
| Less than college | 144 (50.2) | 131 (46.8) | 151 (52.8) | 146 (51.8) | 0.5 |
| College or higher | 143 (49.8 | 149 (53.2 | 135 (47.2 | 136 (48.2 | |
| Smoking status, n (%) | |||||
| Never | 128 (44.6) | 129 (46.1) | 121 (42.3) | 134 (47.5) | 0.06 |
| Former | 137 (47.7 | 133 (47.5 | 125 (43.7 | 124 (44.0 | |
| Current | 22 (7.7 | 18 (6.4 | 40 (14.0 | 24 (8.5 | |
| Diabetes mellitus, n (%) | 51 (17.8) | 37 (13.2) | 39 (13.6) | 62 (22.0) | 0.02 |
| Body mass index (kg/m2), mean (SD) | 26.7 (4.8) | 27.8 (5.1) | 28.4 (5.7) | 30.2 (6.6) | <0.0001 |
| Hypertension, n (%) | 100 (34.8) | 110 (39.3) | 120 (42.0) | 167 (59.2) | <0.0001 |
| LDL-C (mg/dL), mean (SD) | 115.8 (30.6) | 120.9 (28.6) | 128.3 (31.5) | 128.2 (34.6) | <0.0001 |
| HDL-C (mg/dL), mean (SD) | 57.5 (17.3) | 54.9 (15.9) | 53.3 (15.4) | 53.8 (15.5) | 0.01 |
| Triglycerides (mg/dL), median (IQR) | 102.0 (74.0–161.0) | 109.0 (78.5–159.5) | 113.5 (81.0–152.0) | 119.5 (84.0–162.0) | 0.07 |
| Cholesterol lowering drugs, n (%) | 62 (21.6) | 50 (17.9) | 57 (19.9) | 67 (23.2) | 0.4 |
| C reactive protein (mg/dL), median (IQR) | 1.4 (0.5–3.2) | 1.4 (0.6–3.0) | 1.5 (0.7–3.0) | 1.8 (0.8–4.4) | <0.01 |
| Estimated glomerular filtration rate (mL/min/1.73 m2), n (%) | |||||
| <60 | 23 (7.7) | 18 (6.4) | 21 (7.3) | 41 (14.5) | 0.006 |
| 60–89 | 148 (51.6) | 144 (51.4) | 142 (49.7) | 151 (53.6) | |
| 90–130 | 66 (23.0) | 70 (25.0) | 69 (24.1) | 66 (23.4) | |
| >130 | 4 (1.4) | 6 (2.1) | 8 (2.8) | 2 (0.7) | |
| Missing | 47 (16.4) | 42 (15.0) | 46 (16.1) | 22 (7.8) | |
| 10-year Framingham risk score, median (IQR) | 5.7 (1.9–12.1) | 7.1 (2.0–13.8) | 7.0 (1.7–15.1) | 8.2 (2.3–15.6) | 0.02 |