Characteristics of the PRAMI participants and participants in the CMR substudy
| Characteristics | PRAMI preventive | CMR substudy preventive | PRAMI culprit only | CMR substudy culprit only |
|---|---|---|---|---|
| Number of participants | 234 | 42 | 231 | 42 |
| Mean age (range), years | 62 (32–92) | 61 (38–89) | 62 (33–90) | 60 (39–83) |
| Male | 177 (76) | 31 (74) | 186 (81) | 34 (81) |
| Female | 57 (24) | 11 (26) | 45 (19) | 9 (21) |
| Medical history, n (%) | ||||
| Diabetes | 35 (15) | 5 (12) | 48 (21) | 3 (7) |
| Hypertension | 94 (40) | 10 (24) | 93 (40) | 11 (26) |
| Smoker | 118 (50) | 31 (74) | 103 (45) | 26 (62) |
| Previous stroke | 10 (4) | 0 (0) | 10 (4) | 0 (0) |
| Previous myocardial infarction | 19 (8) | 0 (0) | 16 (7) | 1 (2) |
| Blood pressure, mm Hg* | ||||
| Systolic | 136 (26) | 143 (24) | 134 (26) | 142 (29) |
| Diastolic | 81 (14) | 81 (13) | 80 (15) | 85 (17) |
| ST-elevation location, n (%) | ||||
| Anterior | 67 (29) | 10 (24) | 89 (39) | 23 (55) |
| Inferior | 154 (66) | 28 (67) | 128 (55) | 15 (36) |
| Lateral | 10 (4) | 1 (2) | 14 (6) | 2 (5) |
| Coronary arteries with stenosis, n (%) | ||||
| 2 | 143 (61) | 33 (79) | 155 (67) | 30 (71) |
| 3 | 91 (39) | 9 (21) | 76 (33) | 121 (29) |
| Infarct artery, number of stents* | ||||
| Infarct artery* | 1.56 (0.75) | 1.51 (0.60) | 1.42 (0.70) | 1.41 (0.63) |
| Non-infarct artery* | 1.36 (0.77) | 1.38 (0.55) | NA | NA |
| Medical therapy, n (%) | ||||
| Use of glycoprotein IIb/IIIa | 178 (76) | 35 (83) | 176 (76) | 39 (93) |
| Aspirin | 233 (100) | 42 (100) | 229 (100) | 42 (100) |
| Clopidogrel | 234 (100) | 42 (100) | 229 (100) | 42 (100) |
| Statin | 222 (95) | 40 (95) | 223 (97) | 39 (93) |
| β-blocker | 207 (88) | 37 (88) | 210 (92) | 36 (86) |
| ACE inhibitor or angiotensin-receptor blocker | 218 (93) | 39 (93) | 209 (91) | 36 (86) |
The distribution of clinical characteristics was similar between the randomised groups (p>0.05) for all comparisons.
*Mean (SD).
CMR, cardiac magnetic resonance; PRAMI, preventive angioplasty in myocardial infarction.