Diagnostic accuracy of unadjusted and body mass index-adjusted electrocardiogram criteria for anatomic
| Sensitivity (%) | Specificity (%) | Positive predictive value (%) | Negative predictive valve (%) | Diagnostic accuracy (%) | |
|---|---|---|---|---|---|
| Initial cohort (n=821), Sokolow–Lyon index >35 mm (*=p<0.05 for adjusted vs non-adjusted) | |||||
| Total | |||||
| Unadjusted | 14·7 (10·0 to 20·8) | 96·7 (95·1 to 97·8) | 53.2 (38.1 to 67.9) | 81.4 (78.5 to 84.1) | 79.8 |
| Adjusted | 31·4 (24·9 to 38·7)* | 94·7 (92·7 to 96·1)* | 66.25 (54.8 to 76.5) | 84.4 (81.4 to 86.7) | 82.6 |
| Normal weight | |||||
| Unadjusted | 37·8 (24·1 to 53·9) | 92·9 (88·8 to 95·6) | 46.67 (28.3 to 65.7) | 97.1 (95.7 to 98.2) | 85.5 |
| Overweight | |||||
| Unadjusted | 12·8 (6·9 to 22·7) | 98·2 (95·5 to 99·3) | 69.2 (38.6 to 90.9) | 78.6 (73.4 to 83.2) | 78.2 |
| Adjusted | 30·8 (20·2 to 43·3)* | 96·9 (93·8 to 98·8)* | 75.0 (55.1 to 89.3) | 82.5 (77.4 to 86.6) | 81.8 |
| Obese | |||||
| Unadjusted | 3·1 (0·4 to 10.8) | 99·0 (96·4 to 99·9) | 50.0 (6.76 to 93.24) | 76.0 (70.3 to 81.1) | 75.3 |
| Adjusted | 27·2 (18·0 to 39·0)* | 97·9 (94·8 to 99·2)* | 80.9 (58.1 to 94.6) | 81.1 (75.5 to 85.9) | 81.4 |
| Validation cohort (n=520), Sokolow–Lyon index >35 mm (*=p<0.05 for adjusted vs non-adjusted) | |||||
| Unadjusted | 17·9 (8·9 to 28·7) | 97·6 (95·7 to 98·8) | 50.0 (28.2 to 71.8) | 89.4 (86.3 to 91.9) | 87.7 |
| Adjusted | 28.1 (17·6 to 40·8)* | 95.2 (92·8 to 96·9)* | 45.0 (29.3 to 61.6) | 90.4 (87.4 to 92.3) | 86.9 |
| Normal weight | |||||
| Unadjusted | 39·0 (13·9 to 68·2) | 95·4 (91·5 to 97·8) | 35.7 (12.8 to 64.9) | 95.9 (92.1 to 98.2) | 91.9 |
| Overweight | |||||
| Unadjusted | 8·3 (1·1 to 28·0) | 98·6 (95·1 to 99·8) | 50.1 (6.8 to 93.0) | 87.1 (81.0 to 91.9) | 86.2 |
| Adjusted | 39·1 (19·7 to 61·5)* | 93·1 (87·6 to 96·6)* | 47.4 (24.5 to 71.1) | 90.1 (84.5 to 94.7) | 85.6 |
| Obese | |||||
| Unadjusted | 9.4 (1·9 to 25·0) | 99·1 (95·0 to 99·9) | 75.0 (19.4 to 99.4) | 79.0 (71.2 to 85.5) | 78.6 |
| Adjusted | 25·0 (11.5 to 43·4)* | 97·3 (92·2 to 99·4)* | 72.7 (39.0 to 93.9) | 81.5 (73.8 to 87.8) | 81.3 |