Animal weights and CMR characterisation
| Sham, | rTOF, | p Value | |
|---|---|---|---|
| N=4 | N=6 | ||
| Animal weights | |||
| Body weight (kg) | 48±6 | 61±11 | 0.07 |
| BSA (m2) | 0.93±0.07 | 1.05±0.05 | 0.02 |
| Heart weight/BSA (g/m2) | 202±14 | 283±21 | 0.01 |
| RV weight/BSA (g/m2) | 78±4 | 133±16 | 0.02 |
| CMR characterisation | |||
| Heart rate (beats/min) | 117±15 | 98±12 | 0.09 |
| PRF (%) | 0 | 9±7 | 0.03 |
| RV-ESVi (mL/m2) | 37±6 | 122±19 | <0.001 |
| RV-EDVi (mL/m2) | 75±5 | 179±42 | 0.002 |
| RV-SVi (mL/m2) | 39±10 | 57±24 | 0.14 |
| RVEF (%) | 51±11 | 31±6 | 0.03 |
| LVEF (%) | 54±7 | 61±9 | 0.26 |
Data were obtained 23±1 weeks postsurgery. Values are means±SD.
BSA, body surface area; CMR, cardiac magnetic resonance; LVEF, left ventricular ejection fraction; PRF, pulmonary regurgitation fraction; rTOF, repaired tetralogy of Fallot; RV, right ventricular; RV-EDVi, right ventricular end-diastolic volume indexed to BSA; RVEF, right ventricular ejection fraction; RV-ESVi, right ventricular end-systolic volume indexed to BSA; RV-SVi, right ventricular stroke volume indexed to BSA.