Cardiovascular death | ||
Subjects included in analysis* | No ED treatment (n=40 077) | ED treatment (n=3068) |
Number of deaths (%) | 2151 (5.4) | 45 (1.5) |
Incidence rate (cases/100 person years) | 1.61 (1.54 to 1.68) | 0.58 (0.43 to 0.77) |
Unadjusted, HR (95% CI) | Referent | 0.40 (0.30 to 0.54) |
Adjusted for age, HR (95% CI) | Referent | 0.56 (0.42 to 0.76) |
Multivariable adjusted†, HR (95% CI) | Referent | 0.64 (0.47 to 0.86) |
Non-cardiovascular death | ||
Subjects included in analysis* | No ED treatment (n=40 077) | ED treatment (n=3068) |
Number of deaths (%) | 2590 (6.5) | 67 (2.2) |
Incidence rate (cases/100 person years) | 1.93 (1.86 to 2.01) | 0.86 (0.67 to 1.09) |
Unadjusted, HR (95% CI) | Referent | 0.46 (0.36 to 0.59) |
Adjusted for age, HR (95% CI) | Referent | 0.63 (0.49 to 0.81) |
Multivariable adjusted†, HR (95% CI) | Referent | 0.79 (0.68 to 0.92) |
Revascularisation | ||
Subjects included in analysis* | No ED treatment (n=40 443) | ED treatment (n=2702) |
Number of events (%) | 5381 (13.3) | 130 (4.8) |
Incidence rate (cases/100 person years) | 4.54 (4.42 to 4.66) | 1.96 (1.65 to 2.33) |
Unadjusted, HR (95% CI) | Referent | 0.96 (0.81 to 1.15) |
Adjusted for age, HR (95% CI) | Referent | 0.96 (0.80 to 1.14) |
Multivariable adjusted†, HR (95% CI) | Referent | 0.95 (0.80 to 1.14) |
MACE | ||
Subjects included in analysis* | No ED treatment (n=40 522) | ED treatment (n=2623) |
Number of events (%) | 8317 (20.5) | 171 (6.5) |
Incidence rate (cases/100 person years) | 7.37 (7.22 to7.53) | 2.67 (2.30 to 3.11) |
Unadjusted, HR (95% CI) | Referent | 0.72 (0.62 to 0.84) |
Adjusted for age, HR (95% CI) | Referent | 0.76 (0.66 to 0.89) |
Multivariable adjusted†, HR (95% CI) | Referent | 0.79 (0.68 to 0.92) |
* Numbers do not sum up to group total since subjects can be included in the No ED treatment category initially and later change to the ED treatment category
† Adjusted for all variables in table 1, except for medication started the first 6 months following the event which was adjusted for as a time-dependent variable.
MACE, includes hospital stay for MI, or heart failure, or revascularisation.