Results of evaluation of biomarkers and genetic variants using Cox proportional hazard modelling predicting primary endpoint
| Unadjusted analysis | Adjusted analysis* | |||
|---|---|---|---|---|
| Variable | Hazard ratio (95% confidence intervals) | P value | Hazard ratio (95% confidence intervals) | P value |
| BNP (NPX) | 1.42 (1.22–1.65) | <0.0001 | 1.20 (0.99–1.47) | 0.06 |
| Galectin-3 (per 1 ng/ml ) | 1.03 (1.01–1.06) | 0.016 | 1.04 (1.01–1.07) | 0.015^ |
| Troponin I (per pg/ml) | 1.01 (1.01–1.02) | 0.0003 | 1.01 (0.99–1.02) | 0.19 |
| ST2 (NPX) | 0.97 (0.70–1.33) | 0.84 | 0.76 (0.54–1.07) | 0.12 |
| TTNtv present | 0.90 (0.38–2.15) | 0.81 | 0.88 (0.36–2.11) | 0.77 |
| MYH7ms present | 0.67 (0.09–4.84) | 0.69 | 1.37 (0.18 to 10.27) | 0.76 |
| LMNAvar present | 2.84 (0.68–11.78) | 0.15 | 5.73 (1.29–25.46) | 0.02^ |