Relative risks associated with changes in systolic blood pressure and LDL-C.
| Risk factor | Risk factor change | RR for patients with prior myocardial Infarction | Probability distribution around the mean | RR for stroke | Probability distribution around the mean |
| SBP* 12 | 10 mm Hg reduction | 0.76 (0.68 to 0.86) | Normal (0.76, 0.05) | 0.65 (0.53 to 0.80) | Normal (0.65, 0.07) |
| LDL-C11 | |||||
| Men | 1 mmol/L reduction | 0.74 (0.70 to 0.78) | Normal (0.74, 0.02) | 0.83 (0.76 to 0.90) | Normal (0.83, 0.04) |
| Women | 1 mmol/L reduction | 0.83 (0.74 to 0.93) | Normal (0.83, 0.05) | 0.90 (0.78 to 1.04) | Normal (0.83, 0.07) |
| Smoking13 14 | |||||
| Men | Quitting | 0.68 (0.57 to 0.82) | Normal (0.68, 0.06) | 0.60 (0.53 to 0.67) | Normal (0.60, 0.04) |
| Women | Quitting | 0.68 (0.57 to 0.82) | Normal (0.68, 0.06) | 0.55 (0.47 to 0.63) | Normal (0.55, 0.04) |
* Independent of class of blood pressure-lowering drug.
†Independent of type of statin.
For RRs, parentheses contain the 95% CI used for sensitivity analyses. For probability distributions around expected (mean) effects, the first and second values in parentheses correspond to mean and SE in normal distribution.
LDL-C, low-density lipoprotein cholesterol; RR, relative risk; SBP, systolic blood pressure.