Study population, cases and incidence rates of valvular heart disease in Sweden between 2003 and 2010
| Men (n=5 060 355) | Women (n=5 103 856) | |||||||||
| Population | N | Age, years | IQR | IR | 95% CI | N | Age, years | IQR | IR | 95% CI |
| Any VHD | 34582 | 70 | 58–79 | 75.5 | 74.7 to 76.3 | 31221 | 76 | 64–83 | 53.0 | 52.5 to 53.6 |
| Subtypes | ||||||||||
| Aortic stenosis | 18890 | 74 | 64–81 | 37.8 | 37.3 to 38.3 | 17429 | 80 | 72–85 | 24.2 | 23.8 to 24.5 |
| Aortic regurgitation | 8376 | 63 | 43–73 | 20.2 | 19.7 to 20.6 | 5477 | 71 | 57–79 | 10.8 | 10.6 to 11.1 |
| Mitral stenosis | 635 | 64 | 45–76 | 1.5 | 1.4 to 1.6 | 1282 | 74 | 58–81 | 2.3 | 2.2 to 2.5 |
| Mitral regurgitation | 9779 | 69 | 59–77 | 21.3 | 20.9 to 21.7 | 8816 | 74 | 61–81 | 16.0 | 15.7 to 16.4 |
| Pulmonary stenosis | 1109 | 6 | 0–20 | 3.7 | 3.5 to 4.0 | 1351 | 4 | 0–22 | 4.8 | 4.5 to 5.0 |
| Pulmonary regurgitation | 344 | 16 | 8–33 | 1.0 | 0.9 to 1.2 | 293 | 19 | 8–42 | 0.9 | 0.8 to 1.0 |
| Tricuspid stenosis | 151 | 49 | 5–72 | 0.4 | 0.4 to 0.5 | 151 | 62 | 15–76 | 0.4 | 0.3 to 0.4 |
| Tricuspid regurgitation | 1192 | 73 | 62–80 | 2.5 | 2.3 to 2.6 | 1693 | 75 | 65–82 | 2.8 | 2.7 to 3.0 |
| Two concurrent VHD | 3656 | – | – | 8.5 | 8.2 to 8.8 | 3206 | – | – | 5.8 | 5.6 to 6.0 |
| Three or more concurrent VHD | 279 | – | – | 0.7 | 0.6 to 0.8 | 291 | – | – | 0.3 | 0.3 to 0.3 |
Incidence rate (IR) per 1 00 000 person-years at risk between 2003 and 2010 in the Swedish population with 95% CIs. A 3-year washout period was used between 2000 and 2002 to only include incident cases. Age is presented as median age at diagnosis and interquartile range (IQR). VHD, valvular heart disease.