Table 2

Aortic dilation rate between genotype subgroups

ValueHI mutation
(n=98)
DN mutation
(n=150)
pCorr p
Follow-up, years5.0 (2.3)4.9 (1.9)0.960
Aortic dilation rate, mm/year
 Sinus of Valsalva (n=178)0.57 (0.8)0.28 (0.5)0.0080.004
 Tubular ascending aorta (n=131)0.59 (0.9)0.30 (0.7)0.0440.032
 Arch (n=84)0.66 (0.9)0.59 (0.8)0.7320.799
 Proximal descending aorta (n=71)0.61 (0.7)0.42 (1.0)0.4080.403
 Abdominal aorta (n=51)0.50 (0.4)0.49 (0.8)0.9480.912
  • Data are presented as mean and (SD). 

  • Corr P, is the p value corrected for baseline aortic dimension.

  • DN, dominant negative; HI, haploinsufficient.