Table 4

Comparison of the non-laboratory and fasting cholesterol INTERHEART risk scores for predicting cardiovascular disease

NOutcome* (%)Discrimination, C-statistic (95% CI)p Value
NL-IHRSFC-IHRS
Overall85 0781965 (2.31)0.73 (0.72 to 0.74)0.74 (0.73 to 0.75)<0.001
Geographic region
 South Asia7552365 (4.83)0.68 (0.65 to 0.71)0.69 (0.66 to 0.72)0.15
 China35 882549 (1.53)0.69 (0.67 to 0.71)0.69 (0.67 to 0.72)0.81
 Southeast Asia354287 (2.46)0.73 (0.68 to 0.77)0.72 (0.68 to 0.77)0.65
 Africa78939 (4.94)0.65 (0.57 to 0.74)0.68 (0.59 to 0.76)0.49
 North America/Europe15 450500 (3.24)0.69 (0.67 to 0.71)0.72 (0.70 to 0.74)<0.001
 Middle East4763110 (2.31)0.77 (0.72 to 0.81)0.78 (0.73 to 0.82)0.56
 South America17 100315 (1.84)0.72 (0.69 to 0.75)0.73 (0.71 to 0.76)0.26
Country income status
 HIC11 287304 (2.69)0.68 (0.65 to 0.71)0.71 (0.68 to 0.73)0.015
 MIC65 7201266 (1.93)0.73 (0.71 to 0.74)0.73 (0.72 to 0.75)0.12
 LIC8071395 (4.89)0.67 (0.65 to 0.70)0.69 (0.66 to 0.72)0.07
  • *Cardiovascular disease defined as cardiac death, stroke, myocardial infarction, heart failure and revascularisation.

  • FC-IHRS, fasting cholesterol INTERHEART risk score; HIC, high-income countries; LIC, low-income country; MIC, middle-income country; NL-IHRS, non-laboratory INTERHEART risk score; PURE, Prospective Urban Rural Epidemiology.