Selected features of key studies on the management of elderly patients with non-ST-segment elevation acute coronary syndrome (NSTEACS)
| Study | Study category | Patients enrolled | Enrolment years | Troponin elevation | Major bleeding in early invasive vs conservative strategy | Radial access | Use of GPIs | Revascularisation rate in early invasive vs conservative strategy |
| Tegn N et al (After Eighty Study)2 | Randomized trial | 457 | 2010–2014 | 93% | 2% vs 2% | 90% | – | 50% vs 0% |
| Savonitto S et al (Italian Elderly ACS Study)1 | Randomized trial | 313 | 2008–2010 | 61% | 0 vs 1% | 73% | 17% | 51% vs 23% |
| Gierlotka M et al (PL-ACS Registry)4 | Registry | 13707 | 2003–2009 | 100% | 2.9% vs 1.1% | NA | 4.6 | 80.5% vs 0% |
| Devlin G et al (GRACE)5 | Registry | 3029 | 1999–2006 | 82% | 7% vs 3.4% | NA | 15% | – |
| Bauer T et al (ACOS Registry)6 | Registry | 1936 | 2000–2002 | 100% | 8.8% vs 5.8% | NA | 40.2% | 65% vs 0% |
| Damman P et al (FIR Study)7 | Meta-analysis | 839 | 1996–2003 | – | 2.7%* | NA | 25–94%* | 63% vs 16%* |
| Bach RG et al (TACTICS-TIMI 18)8 | Randomized trial | 278 | 1997–1999 | >50% | 16.6% vs 6.5% | NA | 100% | 61.9% vs 32.4% |
GPIs, glycoprotein IIb/IIIa inhibitors; NA, not available.