Table 3

Discrimination and reclassification of CAC for CAD

ModelWomenMen
C-statistic (95% CI)NRIReclassification (%)C-statistic (95% CI)NRIReclassification (%)
Clinical model*0.66 (0.58 to 0.73)0.61 (0.55 to 0.67)
+CAC continuous†0.79 (0.73 to 0.85)0.3324.80.83 (0.78 to 0.87)0.7158.6
+CAC categorical0.78 (0.72 to 0.85)0.2622.50.82 (0.78 to 0.86)0.6962.7
  • *Clinical model includes age, systolic blood pressure, use of blood pressure-lowering medication, total cholesterol, high-density lipoprotein cholesterol and current smoker.

  • †CAC continuous=ln (CAC score+1).

  • CAC, coronary artery calcification; CAD, coronary artery disease; NRI, net reclassification index.