Association of socioeconomic status with changes in heart failure phenotype and treatment over 1 year
| IMD quintile | P value | |||||
| 1 | 2 | 3 | 4 | 5 | ||
| n=60 | n=84 | n=68 | n=83 | n=113 | ||
| Worsening NYHA class (% (n)) | 20 (12) | 11 (9) | 13.2 (9) | 18.1 (15) | 9.9 (11) | 0.27 |
| Change in systolic BP | −3.1 (3.5) | −4.4 (2.6) | 6.5 (3.1) | −0.5 (2.7) | −1.2 (2.6) | 0.6 |
| Change in heart rate | −2.3 (2.5) | −5.5 (2.3) | −5.9 (2.3) | −0.4 (1.9) | −5.8 (2.2) | 0.32 |
| Change in haemoglobin | −0.6 (0.2) | −0.6 (0.1) | −0.5 (0.2) | −0.4 (0.1) | −0.5 (0.2) | 0.82 |
| Change in eGFR | −0.2 (1.0) | −4.2 (1.7) | −1.6 (1.0) | −2.9 (1.0) | −0.4 (1.1) | 0.12 |
| Percent of baseline LV end-systolic dimension | 98.4 (2.5) | 92.8 (2.3) | 95.3 (1.9) | 97.5 (2.1) | 90.4 (1.6) | 0.028 |
| Change in ramipril equivalent dose | 1.3 (0.5) | 1.0 (0.4) | 1.2 (0.3) | 1.0 (0.4) | 1.3 (0.4) | 0.95 |
| Change in bisoprolol equivalent dose | 1.1 (0.5) | 1.8 (0.4) | 2.0 (0.4) | 1.9 (0.3) | 2.0 (0.3) | 0.6 |
| Change in furosemide equivalent dose | −11.9 (5.9) | −3.7 (4.8) | −2.5 (4.8) | 14.6 (5.6) | 0.4 (4.8) | 0.016 |
BP, blood pressure; eGFR, estimated glomerular filtration rate; IMD, Index of Multiple Deprivation; LV, left ventricular; NYHA, New York Heart Association.