Table 2

Change of haemodynamic variables from baseline to follow-up in patients with PAH–CHD

Variable
(n=14)
Change from baselineP value univariateP value multivariate
sPAP (mm Hg)−12.8 (−22.4; −3.2)0.0120.013
dPAP (mm Hg)−3.7 (−9.0; 1.6)n.s.n.s.
mPAP (mm Hg)−8.1 (−14.3; −1.9)0.0150.020
mRAP (mm Hg)−1.5 (−5.2; 2.2)n.s.n.s.
CO (L/min)1.0 (0.5; 1.5)0.0010.002
CI (L/min/m2)0.7 (0.4; 1.0)<0.0010.001
SvO2 (%)−1.3 (−5.9; 3.4)n.s.n.s.
PVR (WU)−5.9 (−9.5; −2.4)<0.0010.003
  • Changes of haemodynamic variables from baseline to follow-up were assessed using linear mixed models. Values are median (25% percentile; 75% percentile) changes from baseline.

  • CHD, congenital heart disease; CI, cardiac index; CO, cardiac output; dPAP, diastolic pulmonary artery pressure; mPAP, mean pulmonary artery pressure; mRAP, mean right atrial pressure; sPAP, systolic pulmonary artery pressure; PAH, pulmonary arterial hypertension; PVR, pulmonary vascular resistance; SvO2, mixed venous saturation; WU, Wood units.