Table 1

Characteristics of the patients with familial hypercholesterolaemia (FH) in the Unit for Cardiac and Cardiovascular Genetics (UCCG) Registry

VariablesTotalMenWomen
Total FH study sample*, n427320622211
 Age at inclusion†, mean (SD)32.7 (18.6)31.2 (18.1)34.1 (18.9)
Study sample with incident AMI‡
 No of patients with FH included in analyses of incident AMI307113941677
 No of patients with FH with first time AMI event996534
 Age at time of first AMI event, mean (SD)56.2 (13.4)54.1 (12.9)60.1 (13.7)
 Years since inclusion in the UCCG Registry to first time AMI event, mean (SD)5.9 (4.8)5.9 (4.9)5.9 (4.6)
Study sample with incident CHD§
 No of patients with FH included in analyses of incident CHD279512271568
 No of patients with FH with first time CHD event253142111
 Age at time of first CHD event, mean (SD)55.1 (13.0)53.1 (12.4)57.7 (13.7)
 Years since inclusion in the UCCG Registry to first time CHD event, mean (SD)6.2 (5.0)6.3 (5.3)6.2 (4.6)
  • *The study sample in the UCCG Registry during 1992–2009.

  • †Age at inclusion in the UCCG Registry equals time at verified genetic FH diagnosis.

  • ‡The study sample in the UCCG Registry with incident acute myocardial infarction (AMI) event during 2001–2009.

  • §The study sample in the UCCG Registry with incident coronary heart disease (CHD) event during 2001–2009.