Table 3

Serial changes in ETT parameters in the total study population

ETT1
(n=316)
ETT2
(n=170)
ETT3
(n=106)
ETT4
(n=67)
ETT final (n=42)Trend
β (95% CI)P vaules
Age, years
  Moderate AS63.7±13.565.2±12.365.2±13.064.3+12.266.7±12.7−0.16 (−0.19 to 0.12)<0.001
  Severe AS69.3±10.969.4±11.569.9±12.967.8±13.956.9±13.5−0.06 (−0.14 to 0.01)0.095
Pre-ETT heart rate, bpm77±1576±1573±1572±1473±14−0.93 (−1.70 to 0.17)0.018
Pre-ETT SBP, mm Hg141±19139±17141±20141±18140±200.22 (−0.89 to 1.32)0.703
Pre-ETT DBP, mm Hg85±1183±1185±1285±1086±120.12 (−0.53 to 0.77)0.719
ETT stage at stopping3.0±1.43.3±1.43.4±1.43.4±1.43.2±1.5−0.06 (−0.14 to 0.01)0.114
Peak heart rate, bpm133±25133±28133±30133±27130±24−2.12 (−3.21, to 1.03)<0.001
Peak SBP, mm Hg167±26163±26164±23165±23158±22−1.35 (−2.73 to 0.04)0.057
Peak DBP, mm Hg90±1690±2089±1688±1589±19−0.90 (−1.97 to 0.16)0.097
THR achieved, %86±1586±1586±1785±1584±14−0.79 (−1.47 to 0.11)0.024
Post-ETT heart rate, bpm84±1386±1683±1782±1480±15−1.45 (-2.45 to 0.45)<0.001
Post-ETT SBP, mm Hg143±21143±21145±23143±18142±190.15 (−1.13 to 1.42)0.824
Post-ETT DBP, mm Hg84±1384±1285±1283±1685±13−0.14 (−1.07 to 0.79)0.763
Exercise duration, min9.7±4.411.0±4.211.8±4.312.7±3.812.6±3.20.25 (0.08 to 0.42)0.005
METs8.6±4.59.1±3.99.3±3.99.6±4.18.9±3.3−0.34 (−0.54 to 0.15)0.001
  • AS, aortic stenosis; DBP, diastolic blood pressure; ETT, exercise treadmill test; METs, metabolic equivalents; SBP, systolic blood pressure; THR, target heart rate.