Multiple logistic regression analysis of the risk factors associated with mitral annular calcification (MAC) and aortic valve calcification without (AVC) or with (CAVS) stenosis, compared with controls
| Risk factors | MAC | AVC | CAVS | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | ||||||
| Age 45–55/<45 years | 8.82 (3.37 to 23.1) | 0.0 | 5.78 (1.13 to 30.6) | 0.03 | 1.11 (0.56 to 2.14) | 0.7 | |||||
| Age 55–65/<45 years | 18.6 (7.54 to 45) | 0.0 | 23.3 (5.33 to 102) | 0.0 | 2.28 (1.30 to 4.0) | 0.0 | |||||
| Age >65/<45 years | 67 (27 to 161) | 0.0 | 104 (24.6 to 440) | 0.0 | 7.7 (4.68 to 12.7) | 0.0 | |||||
| Men/women | 0.45 (0.33 to 0.63) | 0.0 | 0.57 (0.38 to 0.68) | 0.0 | |||||||
| Hypertension | 2.72 (1.92 to 3.86) | 0.0 | 2.38 (1.55 to 3.65) | 0.0 | 1.91 (1.31 to 2.78) | 0.0 | |||||
| Diabetes mellitus | 2.49 (1.4 to 4.14) | 0.0 | 2.85 (1.58 to 5.13) | 0.0 | |||||||
| Hypercholesterolaemia | 2.86 (1.16 to 7.08) | 0.02 | 2.95 (0.99 to 8.82) | 0.05 | 2.55 (0.90 to 7.17) | 0.07 | |||||
| Anterior myocardial infarct | 0.65 (0.41 to 1.03) | 0.06 | 0.47 (0.26 to 0.85) | 0.01 | 0.18 (0.10 to 0.34) | 0.0 | |||||
| Atrial fibrillation | 0.41 (0.16 to 1.02) | 0.05 | |||||||||
| Mitral regurgitation | 0.45 (0.32 to 0.63) | 0.0 | 0.48 (0.31 to 0.74) | 0.0 | |||||||
| Rheumatic mitral stenosis | 2.29 (1.11 to 4.74) | 0.02 | |||||||||
OR, adjusted odds ratio; CI, confidence interval.