Twelve minute walk data on iloprost
| Patient | Diagnosis | Distance (m) | Rest (s) | ΔSaO2(%) | ΔHR (%) | Duration (weeks) | Dose PGI2 (ng/kg/min) |
|---|---|---|---|---|---|---|---|
| 1 | TEPH | 420 | 0 | 0 | 0 | 3.5 | 2.1 |
| 2 | PPH | 740 | 0 | 2 | 50 | 6 | 2.7 |
| 3 | PPH | 880 | 0 | — | — | 8 | 1.0 |
| 4 | TEPH | 340 | 260 | 4.1 | 23.7 | 5 | 1.7 |
| 5 | PPH | 580 | 55 | 13.5 | 15.3 | 7 | 0.7 |
| 6 | TEPH | 580 | 150 | 6 | 20.8 | 11 | 1.6 |
| 7 | PPH | 640 | 0 | 1 | 27.1 | 8 | 3.4 |
| 8 | PPH | 640 | 0 | 46.9 | 32 | 7.5 | 3.9 |
| Mean | 602.5† | 58† | 10.55-150 | 24.15-150 | 7 | 2.1‡ | |
| (SEM) | (60) | (34) | (6.3) | (5.8) | (0.8) | (0.4) |
↵5-150 p < 0.005, †p < 0.001 comparison with baseline;‡p < 0.05 comparison with PGI2 and iloprost dose.
ΔHR (%), percentage increase in heart rate; ΔSaO2(%), percentage drop in oxygen saturation; PPH, primary pulmonary hypertension; TEPH, thromboembolic pulmonary hypertension.