Integrin–ligand interactions
| Adhesion molecule | Other names | Ligand(s) |
|---|---|---|
| β1integrins | ||
| α1β1 | VLA-1, CD49a/CD29 | Laminin (collagen I and IV) |
| α2β1 | VLA-2, CD49b/CD29 | Collagen I and IV (laminin) |
| α3β1 | VLA-3, CD49c/CD29 | Fibronectin, laminin, collagen I, epiligrin, invasin |
| α4β1 | VLA-4, CD49d/CD29 | Fibronectin, VCAM-1, invasin |
| α5β1 | VLA-5, CD49e/CD29 | Fibronectin, invasin |
| α6β1 | VLA-6, CD49f/CD29 | Laminin, invasin |
| α7β1 | – | Laminin |
| α8β1 | – | Vitronectin, fibronectin, tenascin |
| α9β1 | – | Collagen, laminin, tenascin |
| αvβ1 | CD51/CD29 | Fibronectin, vitronectin |
| β2 integrins | ||
| αLβ2 | LFA-1, CD11a/CD18 | ICAM-1, ICAM-2 |
| αMβ2 | Mac-1, CD11b/CD18 | Complement component C3bi, fibrinogen, ICAM-1, factor X |
| αXβ2 | p150,95, CD11c/CD18 | Complement component C3bi, fibrinogen |
| αDβ2 | – | ? |
| β3 integrins | ||
| αIIbβ3 | gpIIbIIIa, CD41/CD61 | Fibrinogen, von Willebrand factor, fibronectin |
| αvβ3 | CD51/CD61 | Vitronectin, thrombospondin, fibrinogen, fibronectin, von Willebrand factor |
| αRβ3 | – | Vitronectin, fibrinogen, fibronectin, von Willebrand factor |
| Other integrins | ||
| α6β4 | – | Laminin/basement membrane |
| αvβ5 | αvβX, αvβS | Vitronectin |
| αvβ6 | – | Fibronectin |
| α4β7 | αvβP, LPAM-1 | Peyers patch, addressin, fibronectin, VCAM-1 |
| αEβ7 | – | E cadherin |
| αvβ8 | – | ? |