Table 2

Laboratory and echocardiographic characteristics of patients with HIV infection (groups I and II) and controls (group III)

VariablesHIV infection
(n = 49)
Controls (n = 58)p value
LVEDD > 5.5 cm (% (n))24.4% (12)3.5% (2)< 0.001
Septal wall thickness (cm)2-150 1.3 (0.3)0.9 (0.2)< 0.001
Left atrial diameter (cm)3.1 (0.5)3 (0.4)NS
LV wall thickness (cm)2-150 1.33 (0.4)1 (0.3)< 0.05
VE (m/s)0.51 (0.1)0.84 (0.1)< 0.001
VA (m/s)0.64 (0.1)0.58 (0.1)< 0.05
Diastolic dysfunction85.7%13.8%< 0.001
(n = 42)(n = 8)
Concentric LV hypertrophy46.9%6.9%< 0.001
(n = 23)(n = 4)
Haemoglobin (g/l)104 (12)134 (16)< 0.05
ESR (mm in 1st hour)39.2 (5.0)25.0 (4.0)< 0.05
CD4+ count (/mm3)233 (57)1043 (112)< 0.001
  • Values are mean (SD) except where specified.

  • 2-150 In diastole.

  • ESR, erythrocyte sedimentation rate; LV, left ventricular; LVEDD, left ventricular end diastolic diameter; VA, peak late velocity; VE, peak early diastolic velocity.