Table 2

Changes in diameter of proximal non-diseased coronary artery segments after application of different nitrate formulations

Mean (SD) artery diameter (mm)
BaselineAfter step 1After step 2
Group 1 (ic/spray)3.2 (1.0)3.6 (0.9)2-150 3.7 (1.1)
Group 2 (ic/caps)3.5 (1.0)3.9 (1.3)2-150 4.0 (1.3)
Group 3 (caps/ic)3.0 (1.0)3.1 (0.9)3.7 (1.0)2-151
Group 4 (spray/ic)3.4 (1.0)3.8 (1.1)2-150 3.9 (1.2)

  • ↵2-150 p < 0.05 artery diameter after step 1 v baseline artery diameter.

  • ↵2-151 p < 0.05 artery diameter after step 2 v artery diameter after step 1.

  • ic, intracoronary nitroglycerin; spray, isosorbide dinitrate spray; caps, sublingual glyceryltrinitrate capsule.