Echocardiographic measurements
| Variable | Controls | Ischaemic | Idiopathic |
|---|---|---|---|
| Left ventricular short axis | |||
| End diastolic dimension (cm) | 4.8 (0.5) | 7.4 (0.6)2-165 | 7.1 (0.6)2-165 |
| End systolic dimension (cm) | 3.0 (0.6) | 6.4 (0.6)2-165 | 6.1 (0.7)2-165 |
| Fractional shortening (%) | 38 (8) | 13 (4)2-165 | 14 (5)2-165 |
| A2–mitral cusp separation (ms) | 60 (20) | 40 (40) | 60 (45) |
| Peak shortening rate (cm/s) | 8.8 (2.9) | 4.9 (1.3)2-165 | 4.5 (2.1)2-165 |
| Peak lengthening rate (cm/s) | 9.4 (3.0) | 6.6 (3.2)* | 6.1 (2.8)* |
| Left ventricular long axis | |||
| Lateral | |||
| Excursion (cm) | 1.5 (0.3) | 0.9 (0.3)2-165 | 0.9 (0.3)2-165 |
| Peak shortening rate (cm/s) | 7.3 (1.9) | 4.3 (1.3)2-165 | 4.7 (0.8)2-165 |
| Peak lengthening rate (cm/s) | 7.7 (1.7) | 4.9 (2.8)* | 5.4 (3.0)* |
| Septal | |||
| Excursion (cm) | 1.4 (0.3) | 0.6 (0.3)2-165 | 0.7 (0.3)2-165 |
| Peak shortening rate (cm/s) | 6.1 (1.4) | 2.9 (1.8)2-165 | 3.4 (1.3)2-165 |
| Peak lengthening rate (cm/s) | 6.5 (2.1) | 3.1 (2.2)2-165 | 4.7 (1.8) |
| Posterior | |||
| Excursion (cm) | 1.6 (0.3) | 0.9 (0.2)2-165 | 1.0 (0.3)2-165 |
| Peak shortening rate (cm/s) | 6.5 (1.3) | 4.0 (1.4)2-165 | 4.0 (1.7)2-165 |
| Peak lengthening rate (cm/s) | 7.9 (2.1) | 5.2 (2.2)** | 4.5 (2.2)** |
| Right ventricular long axis | |||
| Excursion (cm) | 2.6 (0.3) | 1.6 (0.5)2-165 | 2.4 (0.5)†† † |
| Peak shortening rate (cm/s) | 12.1 (1.6) | 8.6 (3.0)** | 11.3 (3.5)† |
| Peak lengthening rate (cm/s) | 10.1 (3.1) | 8.5 (2.7) | 10.2 (3.6) |
Values are mean (SD). A2–mitral cusp separation, M mode isovolumic relaxation time measured as the interval between the first high frequency component on the phonocardiogram and the separation of the mitral valve leaflets on the mitral M mode echocardiogram.
↵2-165 p<0.001, **p<0.01, *p<0.05 v controls;†† †p<0.001, †p<0.05 v ischaemic group.