Plasma neurohormone concentrations and left ventricular indices measured one to four days after myocardial infarction in patients with and without subsequent adverse events over a mean 14 month follow up
| n | BNP (pmol/l) | ANF (pmol/l) | N-ANF (pmol/l) | cGMP (nmol/l) | Adrenaline (pmol/l) | Noradrenaline (nmol/l) | LVEF (%) | LVEDV (ml) | LVESV (ml) | |
|---|---|---|---|---|---|---|---|---|---|---|
| Death | ||||||||||
| Yes | 26 | 52 (35)*** | 68 (66)*** | 4054 (2333)*** | 8.5 (5.8)*** | 210 (112) | 2.84 (1.79)3-150 | 35 (16)*** | 203 (86)*** | 140 (73)*** |
| No | 194 | 29 (17) | 34 (22) | 2064 (1346) | 6.0 (2.6) | 204 (174) | 2.19 (1.19) | 47 (12) | 147 (38) | 79 (32) |
| Heart failure | ||||||||||
| Yes | 56 | 50 (30)*** | 65 (51)*** | 3640 (2113)*** | 8.8 (4.6)*** | 256 (160)3-150 | 3.20 (1.68)*** | 36 (15)*** | 183 (69)*** | 122 (59)*** |
| No | 164 | 25 (12) | 29 (14) | 1841 (1074) | 5.5 (2.0) | 188 (169) | 1.95 (0.96) | 49 (10) | 144 (35) | 75 (27) |
| Acute coronary syndrome | ||||||||||
| Yes | 66 | 34 (23) | 40 (41) | 2448 (1618) | 6.5 (3.6) | 174 (116) | 2.26 (1.15) | 46 (15) | 149 (49) | 84 (44) |
| No | 154 | 31 (20) | 37 (28) | 2236 (1848) | 6.3 (3.2) | 218 (194) | 2.27 (1.39) | 46 (13) | 156 (55) | 88 (48) |
Values are mean (SD).
↵3-150 p < 0.05; ***p < 0.001, comparison of those with and without event.
ANF, atrial natriuretic factor; BNP, brain natriuretic peptide; cGMP, cyclic guanosine monophosphate; LVEDV, left ventricular end diastolic volume; LVEF, left ventricular ejection fraction; LVESV, left ventricular end systolic volume; NA, noradrenaline; N-ANF, N-terminus ANF.