Patient characteristics and treatments according to diuretic use at randomisation
| Variable | Not on diuretic (n = 798) | On diuretic (n = 1188) | p Value |
|---|---|---|---|
| Mean (SD) age (years) | 62.8 (11.4) | 66.6 (10.0) | < 0.001 |
| Digitalis | 48 (6.0) | 195 (16.4) | < 0.001 |
| β Blocker | 213 (26.7) | 230 (19.4) | < 0.001 |
| Thrombolysis | 500 (62.7) | 642 (54.0) | < 0.001 |
| Nitrates | 412 (62.7) | 697 (58.7) | 0.002 |
| Multiple clinical signs of heart failure | 375 (47.5) | 634 (53.5) | 0.01 |
| Radiographic | 393 (49.7) | 635 (53.6) | 0.09 |
| Rales | 661 (83.6) | 1043 (88.1) | 0.005 |
| S3 gallop | 189 (23.9) | 293 (24.7) | 0.66 |
| Past medical history | |||
| Myocardial infarction | 155 (19.4) | 293 (24.7) | 0.006 |
| Heart failure | 53 (6.6) | 110 (9.3) | 0.04 |
| Arrhythmia | 41 (5.2) | 81 (6.8) | 0.13 |
| Angina | 268 (33.6) | 440 (37.0) | 0.13 |
| Hypertension | 220 (27.6) | 334 (28.1) | 0.79 |
| Diabetes mellitus | 95 (11.9) | 145 (12.2) | 0.84 |
| Sex (male) | 608 (76.2) | 853 (71.8) | 0.03 |
| Mean (SD) LVEF (%) | 38 (14.3) | 40 (15.0) | 0.09 |
| Ramipril | 418 (52.4) | 586 (49.3) | 0.19 |
| Aspirin | 628 (78.7) | 915 (77.0) | 0.38 |
| Calcium antagonists | 121 (15.0) | 196 (16.5) | 0.43 |
| Location of infarct | |||
| Anterior | 462 (57.9) | 689 (58.0) | 0.96 |
| Inferior | 305 (38.2) | 434 (36.5) | 0.45 |
| ECG classification: Q wave | 491 (63.8) | 715 (63.2) | 0.81 |
Values in parentheses are percentages unless otherwise stated.
LVEF, left ventricular ejection fraction.