Mortality and severe/resistant heart failure (SRHF) outcomes by baseline clinical features in 1986 patients
| Total mortality hazard ratios (95% CI) | SRHF hazard ratios (95% CI) | |
|---|---|---|
| Past medical history of heart failure | 1.76 (1.31 to 2.38) | 2.17 (1.57 to 3.01) |
| p Value | < 0.001 | < 0.001 |
| Past medical history of diabetes mellitus | 1.60 (1.23 to 2.10) | 1.25 (0.92 to 1.71) |
| p Value | < 0.001 | 0.16 |
| S3 gallop | 1.46 (1.16 to 1.85) | 1.72 (1.33 to 2.22) |
| p Value | 0.016 | < 0.001 |
| Left ventricular ejection fraction < 39% | 1.42 (0.93 to 2.18) | 1.41 (0.90 to 2.23) |
| p Value | 0.10 | 0.14 |
| Digoxin | 1.41 (1.07 to 1.86) | 1.19 (0.87 to 1.63) |
| p Value | 0.014 | 0.28 |
| Diuretics | 1.37 (1.08 to 1.73) | 1.50 (1.16 to 1.96) |
| p Value | 0.009 | 0.024 |
| Past medical history of angina | 1.34 (1.06 to 1.68) | 1.18 (0.91 to 1.53) |
| p Value | 0.013 | 0.22 |
| Anterior myocardial infarction | 1.28 (1.03 to 1.61) | 1.11 (0.35 to 3.53) |
| p Value | 0.029 | 0.83 |
| Radiographic evidence of heart failure | 1.22 (0.98 to 1.51) | 1.27 (1.00 to 1.62) |
| p Value | 0.078 | 0.048 |
| Past medical history of myocardial infarction | 1.08 (0.85 to 1.39) | 1.46 (1.12 to 1.91) |
| p Value | 0.55 | 0.005 |
| Age (per 1 year) | 1.03 (1.02 to 1.04) | 1.02 (1.01 to 1.04) |
| p Value | < 0.001 | < 0.001 |
| Ramipril | 0.80 (0.65 to 0.99) | 0.82 (0.65 to 1.04) |
| p Value | 0.041 | 0.09 |
| Thrombolysis | 0.68 (0.55 to 0.85) | 0.75 (0.59 to 0.96) |
| p Value | < 0.001 | 0.02 |
| β Blockers | 0.66 (0.48 to 0.90) | 0.58 (0.40 to 0.83) |
| p Value | 0.008 | 0.003 |
Hazard ratios derived by multivariate analysis with either total mortality or severe/resistant heart failure as an end point in the entire AIRE study population. Covariates were included in this table if p ⩽ 0.1 for at least one analysis and were ordered by size of hazard ratio for total mortality analysis.