Study | Number of cases/controls2-150 (description of case tissue) | Case and controls positive for C pneumonia2-150 | |||
---|---|---|---|---|---|
PCR | ICC | Other | |||
Controlled studies. Age, tissue, and diagnostic method matched | |||||
Kuo (1995)51 | 18v 31 (coronary artery) | 17%v 0% | 39% v0% | ||
Maass (1997)50 | 61v 39 (carotid endarterectomy) | 15%v 0% | |||
Petersen (1998)61 | 40 v 40 (AAA) | 35% v5% | |||
Other controls | |||||
Grayston2-151 (1995)62 | 5v 0 (carotid endarterectomy) | 60% | 100% | ||
56 v6 (archival or necropsy carotid specimens) | 57%v 0% | ||||
Ong2-151(1995)55 | 32 AAA repairs v 6 patients with normal vascular tissue | 44%v 50% | 3/8 (38%)v not done | ||
Jackson (1997)63 | 38 v 38 (vascularv non-vascular tissue from necropsy cases) | 16% v 0–8% | 24%v 5–11% | ||
Juvonen (1997)64 | 12 v 9 (abdominal aortic aneurysm) | 6/6 v 0/9 | 100%v 0% | ||
Kuo2-151(1997)65 | 23 v 8 (diseased femoral and popliteal arteries) | 48%v 0% | 0%‡ vnot done | ||
Maass2-151 (1998)48 | 70v 17 (coronary atherectomy, failed grafts and other vessels) | 30% v0% | 16%‡ v not done | ||
Wong (1998)54 | 58 v 58 (coronary atherectomy and failed grafts) | 39% v12–30% | |||
Shor (1992)66 | 10v 5 (coronary artery) Cases were highly selected from 1000 arteries | 5/7 (71%)v 0/5 (0%) | 10/10§ v not done | ||
Kuo (1993)67 | 20 v 4 (aortic atheroma) | 30% v 0% | |||
Chiu2-151(1997)58 | 76 v 20 (carotid and aortic tissue) | 71% v0% | |||
Muhlestein2-151 (1996)68 | 90 coronary atherectomies 24 other controls | 79%v 4.2%¶ | |||
Studies without controls | |||||
Kuo (1993)60 | 36 (coronary artery) | 13/30 (43%) | 15/36 (42%) | 6/21§ (29%) | |
Campbell (1995)59 | 37 (coronary atherectomy) | 32% | 45% | 2/2§ | |
Ramirez (1996)46 | 12 (coronary artery) | 41.7% | 41.7% | 8%‡ 25%§ | |
Jackson (1997)47 | 25 (carotid endarterectomy) | 24% | 8/16 (50%) | 4%‡ | |
Blasi (1996)69 | 51 (AAA) | 51% | |||
Weiss (1996)18 | 72 (coronary atherectomies) | 1/50 (2%) | 0/22‡ § | ||
Davidson (1998)56 | 60 (coronary artery) | 14/60 (23.3%) | 20/60 (33.3%) | ||
Bauriedel (1998)57 | 32 (carotid and coronary arteries) | 47% | |||
Lindholt (1998)52 | 20 (AAA) | 0% | |||
Paterson (1998)53 | 30 (carotid and coronary arteries) | 0% | |||
Saldeen (1998)45 | 60 (coronary arteries) | 62% |
↵2-150 In some cases, more than one specimen was obtained from each patient. In these cases and where it was possible to determine from the papers, results are expressed as positive patients per number of patients.
↵2-151 Studies where control vessels did not come from age matched subjects or where control subjects were poorly described; ‡culture; §electron microscopy; ¶direct immunofluorescence.
PCR, polymerase chain reaction; ICC, immunocytochemistry; AAA, abdominal aortic aneurysm; IMA, internal mammary artery.