Table 2

Cardiovascular risk factors and adjusted relative risk of major CHD events over 15 years’ cumulative duration of follow up in 7198 men with no diagnosed CHD (799 cases) and with available data on all lifestyle covariates

Coronary risk factors	Adjusted relative risk (95% CI)
Lifestyle and pre-existing disease^2-151
Smoking
Ex (v never)	1.5 (1.2 to 2.8)^***
Current (v never)	2.3 (1.9 to 2.9)^***
BMI (⩾ 28 v < 22 kg/m²)	1.8 (1.4 to 2.3)^***
Alcohol (light/moderatev occasional)	0.8 (0.7 to 0.9)^**
Physical activity (moderate vnone)	0.5 (0.4 to 0.7)^***
Parental history (yes/no)	1.5 (1.3 to 1.8)^***
Pre-existing CHD (no diagnosis)	1.6 (1.4 to 1.8)^***
Diabetes (yes/no)	2.2 (1.5 to 3.3)^**
Biological factors^2-152
Systolic blood pressure^2-153	1.9 (1.5 to 2.4)^***
Diastolic blood pressure^2-153	1.8 (1.4 to 2.3)^***
Cholesterol^2-153	2.5 (2.0 to 3.2)^***
HDL cholesterol^2-153	0.6 (0.5 to 0.7)^***
Glucose (⩾ 6.2 mmol/lv rest)	1.2 (0.9 to 1.4)
Insulin (top decile v rest)	1.5 (1.2 to 1.9)^***

Test for difference/trend: ^*p < 0.05; ^**p < 0.01; ^***p < 0.001.
↵2-151 Adjusted for age, lifestyle factors, diabetes and pre-existing CHD (without diagnosis).
↵2-152 Adjustments made in addition for systolic blood pressure and total cholesterol.
↵2-153 Top quartile v bottom quartile.