Efficacy of carvedilol after three months of treatment
| Amiodarone | No amiodarone | p Value | |
|---|---|---|---|
| Symptomatic outcome | |||
| Improved | 31 (39%) | 67 (45%) | NS |
| Unchanged | 28 (35%) | 51 (34%) | NS |
| Worse | 21 (26%) | 32 (21%) | NS |
| Change in 6 minute walk distance (m) | + 52 (14)3-165 | + 43 (8)3-168 | NS |
| Echocardiographic changes | |||
| LVEDD (mm) | −1.2 (0.8) | −1.8 (0.5)3-165 | NS |
| LVESD (mm) | −3.3 (0.9)3-165 | −3.5 (0.6)3-168 | NS |
| LVFS (%) | +3.3 (0.7)3-168 | +3.0 (0.6)3-168 | NS |
| LVEF (%) | +5.5 (1.2)3-168 | +5.1 (1.0)3-168 | NS |
NS, non-significant (for between group comparisons);
↵3-165 p < 0.001;
↵3-168 p < 0.0001 compared to baseline (for within group comparisons).
LVEDD, left ventricular end diastolic dimension; LVESD, left ventricular end systolic dimension; LVFS, left ventricular fractional shortening; LVEF, left ventricular ejection fraction.