Trial | Primary end point | Other end points |
Mild | Progression of CHF4-150 | LVEF4-150, NYHA class4-150, HF score4-150, global assessment4-150, QoL, 9 min SPT, heart size on CXR (death4-150) |
Moderate (MOCHA) | 6 min walk 9 min SPT | LVEF4-150, CHF hospitalisation4-150, (QoL, global assessment, death4-150) |
Moderate (PRECISE) | 6 min walk4-150
9 min SPT | Global assessment4-150, NYHA class4-150, LVEF4-150, QoL, CV hospitalisation4-150 |
Severe | QoL | Death, CV hospitalisation, global assessment4-150, NYHA class, LVEF4-150, 6 min walk |
↵4-150 Significant, between group, difference; CV, cardiovascular; CXR, chest radiography; HF, heart failure score; QoL, quality of life; SPT, self powered treadmill; for rest of key see text.