No events (n = 71) | Events (n = 11) | p Value | |
Demographics | |||
Age (years) | 65.1 (8.3) | 68.0 (12.3) | 0.46 |
Systolic blood pressure (mm Hg) | 140.5 (23.3) | 129.5 (19.8) | 0.16 |
Diastolic blood pressure (mm Hg) | 82.5 (10.3) | 77.5 (13.2) | 0.17 |
Body mass index (kg/m2) | 27.3 (4.5) | 27.4 (4.4) | 0.96 |
Menopausal women, n (%) | 66 (93.0) | 10 (90.9) | 1.00 |
Risk factors | |||
Diabetes mellitus, n (%) | 3 (4.2) | 1 (9.1) | 0.44 |
Dislipidaemia, n (%) | 40 (56.3) | 6 (54.6) | 0.99 |
Hypertension, n (%) | 29 (40.8) | 6 (54.5) | 0.39 |
Peripheral vascular disease, n (%) | 9 (12.7) | 1 (9.1) | 1.00 |
Previous myocardial infarction, n (%) | 3 (4.2) | 2 (18.2) | 0.13 |
Active smoking, n (%) | 36 (50.7) | 3 (27.3) | 0.20 |
Baseline treatment | |||
Nitrates, n (%) | 36 (50.7) | 8 (72.7) | 0.21 |
Aspirin, n (%) | 50 (70.4) | 8 (72.7) | 1.00 |
β blocker, n (%) | 43 (60.6) | 6 (54.5) | 0.71 |
ACE inhibitor, n (%) | 12 (16.9) | 3 (27.3) | 0.41 |
Lipid lowering, n (%) | 15 (21.1) | 4 (36.4) | 0.27 |
Diuretic, n (%) | 17 (23.9) | 5 (45.5) | 0.13 |
Hormone replacement therapy, n (%) | 17 (24.6) | 0 | 0.11 |
Coronary angiography | |||
0 vessel disease, n (%) | 25 (35.2) | 0 | |
1 vessel disease, n (%) | 26 (36.6) | 5 (45.5) | |
2 vessel disease, n (%) | 13 (18.3) | 3 (27.3) | |
3 vessel disease, n (%) | 7 (9.9) | 3 (27.3) | 0.014 |
Left ventricular ejection fraction (%) | 69.1 (7.4) | 62.5 (16.0) | 0.20 |
Biochemistry | |||
Total cholesterol (mmol/l) | 6.40 (1.25) | 6.39 (1.40) | 0.99 |
Triglycerides (mmol/l) | 1.40 [1.10—2.00] | 1.70 [1.15—3.15] | 0.010 |
HDL cholesterol (mmol/l) | 1.07 (0.27) | 1.05 (0.27) | 0.83 |
LDL cholesterol (mmol/l) | 4.55 (1.28) | 4.09 (1.39) | 0.27 |
LDL/HDL ratio | 4.69 (2.30) | 4.11 (1.45) | 0.43 |
Neopterin (nmol/l) | 5.70 (3.90–7.25) | 7.10 (6.95–9.10) | 0.0232-150 |
C reactive protein (mg/l) | 2.90 (1.25–5.65) | 4.60 (3.20–9.90) | 0.19 |
Haematology | |||
Whole blood cell count (× 109/l) | 7.36 (1.48) | 7.50 (1.08) | 0.84 |
↵2-150 Corrected by creatinine; quantitative variables are expressed as mean (SD) or median (interquartile interval); qualitative variables are expressed as n (%).