Factors associated with mortality: univariate analysis
| Factors | No death | Death | p Value |
| Total number of events | 180 (85) | 32 (15) | |
| Male sex | 136 (76) | 24 (75) | NS |
| Mean (SD) age (years) | 51 (18) | 61 (16) | 0.005 |
| Cardiac risk factor(s) | 116 (64) | 17 (53) | NS |
| Non-cardiac risk factor(s) and underlying conditions | 66 (37) | 19 (59) | < 0.02 |
| Intravenous drug use | 20 (11) | 2 (6) | NS |
| Pre-existing renal insufficiency | 26 (14) | 11 (34) | < 0.007 |
| Mean (SD) number of symptoms on admission | 5 (2) | 4 (2) | < 0.03 |
| Neurological signs on admission | 34 (19) | 15 (47) | 0.0005 |
| Neurological signs during IE | 55 (31) | 22 (69) | < 0.0001 |
| Congestive heart failure during IE | 69 (38) | 19 (59) | < 0.03 |
| Weight loss during IE | 68 (38) | 8 (25) | < 0.04 |
| Fatigue during IE | 125 (69) | 14 (44) | < 0.005 |
| Arthralgia during IE | 51 (28) | 3 (9) | < 0.02 |
| Vascular phenomena during IE | 98 (54) | 16 (50) | NS |
| Valve perforation | 52 (29) | 11 (34) | NS |
| Vegetation | 120 (67) | 23 (72) | NS |
| Abscess in echocardiography | 10/171 (6) | 6/22 (27) | 0.0006 |
| Anticoagulation3-150 | 99 (55) | 16 (50) | NS |
| Anaemia during IE | 164 (91) | 28 (88) | NS |
| Mean (SD) C reactive protein (mg/l) | 99 (63) | 177 (108) | 0.0007 |
Values are n (%) unless otherwise specified.
↵3-150 Started within 30 days of initiation of antibiotic treatment.
IE, infective endocarditis, NS, not significant.