Clinical characteristics of SPECT substudy patients
| Time to thrombolysis | |||||
|---|---|---|---|---|---|
| < 2 hours (n=316) | 2–4 hours (n=406) | 4–6 hours (n=217) | > 6 hours (n=160) | p Value | |
| Age (years) | 57 (11) | 59 (12) | 59 (12) | 58 (11) | 0.036 |
| Male sex | 84% | 79% | 74% | 75% | 0.029 |
| History | |||||
| Angina | 31% | 37% | 30% | 40% | 0.077 |
| MI | 18% | 15% | 11% | 16% | 0.13 |
| PTCA or CABG | 9% | 6% | 7% | 8% | 0.48 |
| Hypertension | 37% | 42% | 42% | 50% | 0.05 |
| Diabetes | 14% | 17% | 12% | 19% | 0.21 |
| Never smoked | 28% | 29% | 34% | 35% | 0.015 |
| Anterior infarct | 40% | 41% | 37% | 44% | 0.59 |
| Type of thrombolysis | |||||
| t-PA | 40% | 29% | 18% | 17% | < 0.001 |
| Streptokinase | 60% | 71% | 82% | 83% | |
| Other | 0% | 0% | 0% | 1% | |
| β Blockers before randomisation | 19% | 24% | 22% | 26% | 0.32 |
| At presentation: | |||||
| Heart rate (beats/min) | 73 (17) | 78 (16) | 77 (16) | 81 (21) | 0.17 |
| Diastolic BP (mm Hg) | 82 (16) | 82 (15) | 81 (15) | 83 (16) | 0.40 |
| Systolic BP (mm Hg) | 132 (24) | 133 (24) | 131 (22) | 134 (24) | 0.58 |
| HR × diastolic BP | 6047 (2160) | 6414 (2001) | 6256 (1936) | 6843 (2643) | 0.002 |
| HR × systolic BP | 9701 (3478) | 10 448 (3173) | 10 196 (3105) | 10 965 (4060) | < 0.001 |
Data are expressed as mean (SD) or as percentage of patients.