Patient | Cardiac lesions | Chromosomes |
1 | HLHS | N |
2 | HLHS | N |
3 | HLHS | N |
4 | HLHS | N |
5 | HLHS | N |
6 | HLHS-EFE, tiny LV | N |
7 | LV hypoplasia, aortic hypoplasia, LVH+ | N |
8 | Critical aortic stenosis—very small LV, EFE | N |
9 | Hypoplastic LV, DORV, mitral atresia | N |
10 | Tetralogy of Fallot, small LV, pulmonary atresia, cleft lip and palate | N |
11 | Multiple VSDs, cleft lip and palate | N |
12 | Severe Ebstein's anomaly | Translocation, chromosome 10 |
13 | TGA, pulmonary atresia, renal agenesis | N |
14 | Large confluent VSD, severe aortic hypoplasia, tetralogy of Fallot | Trisomy 18 |
15 | Perimembranous VSD, pulmonary atresia | Trisomy 21 |
16 | CAVSD, hypoplastic LV | Trisomy 21 |
17 | CAVSD, hypoplastic LV, DORV | Trisomy 21 |
18 | CAVSD, hypoplastic LV | Partial deletion, chromosome 6 |
19 | CAVSD, hypoplastic LV, TGA | N |
20 | CAVSD, pulmonary atresia | N |
21 | CAVSD, TGA | N |
22 | CAVSD, LVOTO, renal agenesis | N |
23 | PAVSD, hypoplastic LV | Trisomy 21 |
Total: five major and two minor chromosomal problems, two lethal non-cardiac abnormalities, three non-cardiac surgical abnormalities.
CAVSD, complete atrioventricular septal defect; DORV, double outlet right ventricle; EFE, endocardial fibroelastosis; HLHS, hypoplastic left heart syndrome; LV, left ventricle; LVH, left ventricular hypertrophy; LVOTO, left ventricular outflow tract obstruction; N, normal; PAVSD, partial atrioventricular septal defect; TGA, transposition of the great arteries.