Table 1

Baseline clinical characteristics of current smokers, ex-smokers, and non-smokers

Non-smokers Ex-smokers Current smokers Significance level
Number of patients7281690530
Men65.3%87.5%1-150 85.9%1-150 0.000
Age (years) (mean (SD))59.9 (9.4)57.0 (9.1)1-150 54.0 (9.0) 0.000
Previous myocardial infarct37.9%43.9%1-150 42.9%1-150 0.022
Previous CABG3.6%4.6%4.0%0.470
Previous PTCA4.1%5.1%5.5%0.486
Diabetes mellitus12.6%9.5%1-150 9.1%1-150 0.043
IDDM1.8%0.7%1-150 0.4%1-150 0.009
History of hypertension37.2%29.3%1-150 24.9%1-150 0.000
History of hypercholesterolaemia32.0%31.5%31.9%0.965
History of PVD2.3%5.5%1-150 7.2%1-150 0.000
Anginal class
 None6.3%5.8%4.3%
 CCS class I9.8%11.7%11.3%
 CCS class II34.6%32.6%29.4%
 CCS class III31.5%29.9%29.1%
 CCS class IV17.9%20.2%25.9%1-150 1-151 0.032
Duration of angina (weeks) (mean (SD))120 (208)111 (209)94 (202)0.205
Days since deterioration of angina (mean (SD))80 (198)79 (181)65 (127)0.524
Drug treatment at screening
 β Blockers52.3%49.2%51.5%0.321
 Calcium antagonists65.4%70.4%1-150 72.3%1-150 0.016
 Nitrates62.1%66.7%66.2%0.659
 Anticoagulants0.8%1.5%2.5%0.067
 Platelet inhibitor64.3%63.5%67.7%0.203
 Aspirin77.9%83.4%1-150 83.1%1-150 0.032
 Persantin10.6%11.6%15.2%0.121
Laboratory investigations (mean (SD))
 Haemoglobin (g/dl)8.72 (0.86)8.89 (0.80)8.99 (0.86)1-150 0.000
 Packed cell volume (%)41 (4)42 (4)43 (4)1-150 0.000
 White cell count (G/l)7.05 (2.94)7.34 (2.09)8.26 (2.24)1-150 1-151 0.000
 Platelet count (G/l)260 (80)255 (66)258 (70)0.276
 Total cholesterol (mmol/l)5.88 (1.31)5.80 (1.21)5.88 (1.20)0.249
 HDL cholesterol (mmol/l)1.20 (0.34)1.13 (0.56)1.11 (0.69)0.477
 LDL cholesterol (mmol/l)4.15 (1.18)4.16 (1.33)3.94 (1.20)0.519
  • 1-150 p < 0.05 v non-smokers;

  • 1-151 p < 0.05 v ex-smokers.

  • CABG, coronary artery bypass graft; HDL, high density lipoprotein; IDDM, insulin dependent diabetes mellitus; LDL, low density lipoprotein; PTCA, percutaneous transluminal coronary angioplasty; PVD, peripheral vascular disease.