Rest and exercise measurements in patients with (CR+) and without (CR−) contractile reserve)
| Rest | Exercise | |||||||
|---|---|---|---|---|---|---|---|---|
| CR− | CR+ | p Value | CR− | CR+ | p Value | |||
| A. Medically treated patients | ||||||||
| LVIDD (mm) | 53 (9) | 57 (5) | 0.15 | 52 (7) | 52 (6) | 0.67 | ||
| LVIDS (mm) | 37 (7) | 39 (5) | 0.32 | 34 (6) | 35 (6) | 0.87 | ||
| Fractional shortening (%) | 31 (7) | 32 (5) | 0.69 | 35 (6) | 33 (8) | 0.40 | ||
| LVEDV (ml) | 136 (37) | 161 (43) | 0.08 | 122 (44) | 146 (46) | 0.13 | ||
| LVESV (ml) | 54 (15) | 71 (22) | 0.01 | 58 (21) | 54 (19) | 0.58 | ||
| Ejection fraction (%) | 60 (5) | 56 (6) | 0.02 | 52 (5) | 63 (7) | 0.0001 | ||
| Contractile reserve (ΔEF) | −8 (4) | 7 (3) | 0.0001 | |||||
| Exercise time (min) | 8 (2) | 10 (3) | 0.06 | |||||
| Exercise capacity (METs) | 8 (2) | 10 (3) | 0.03 | |||||
| Peak heart rate (beats/min) | 149 (22) | 160 (21) | 0.13 | |||||
| % Predicted heart rate | 90 (9) | 93 (10) | 0.42 | |||||
| Peak systolic BP (mm Hg) | 201 (38) | 196 (34) | 0.66 | |||||
| Rate–pressure product (×1000) | 29.8 (6.5) | 31.5 (7.0) | 0.50 | |||||
| B. Surgically treated patients | ||||||||
| LVIDD (mm) | 55 (7) | 57 (8) | 0.61 | 52 (7) | 54 (9) | 0.47 | ||
| LVIDS (mm) | 40 (6) | 41 (7) | 0.83 | 39 (6) | 38 (8) | 0.89 | ||
| Fractional shortening (%) | 27 (4) | 28 (5) | 0.54 | 26 (4) | 30 (7) | 0.07 | ||
| LVEDV (ml) | 161 (49) | 193 (79) | 0.22 | 143 (40) | 175 (75) | 0.19 | ||
| LVESV (ml) | 72 (28) | 101 (53) | 0.10 | 73 (26) | 78 (46) | 0.74 | ||
| Ejection fraction (%) | 56 (6) | 48 (7) | 0.008 | 49 (6) | 57 (7) | 0.006 | ||
| Contractile reserve (ΔEF) | −7 (5) | 9 (6) | 0.0001 | |||||
| Exercise time (min) | 10 (2) | 9 (3) | 0.31 | |||||
| Exercise capacity (METs) | 9 (2) | 8 (2) | 0.41 | |||||
| Peak heart rate (beats/min) | 156 (20) | 147 (25) | 0.32 | |||||
| % Predicted heart rate | 98 (8) | 89 (13) | 0.06 | |||||
| Peak systolic BP (mm Hg) | 214 (22) | 197 (46) | 0.23 | |||||
| Rate–pressure product (×1000) | 33.2 (4.9) | 28.7 (7.4) | 0.08 | |||||
Values are mean (SD).
BP, blood pressure; ΔEF, change in ejection fraction on follow up; LVEDV, left ventricular end diastolic volume; LVESV, left ventricular end systolic volume; LVIDD, left ventricular internal diameter in diastole; LVIDS, left ventricular internal diameter in systole; METs, metabolic equivalents on exercise.