Table 2

Left ventricular mass and diastolic variables in healthy controls and patients infected by HIV

VariableHealthy controls (n=32)HIV infected patients
Overall
(n=61)		Well nourished (n=35)Malnourished (n=26)
Left ventricular mass (g)222.5 (44.8)132.4 (44.3)2-c 147.5 (49.0)2-c 112.1 (26.5)2-c 2-e
Left ventricular mass index (g/m2)118.8 (23.5)76.7 (23.6)2-c 83.3 (26.7)2-c 67.8 (14.8)2-c 2-d
Left ventricular diastolic diameter (mm)45.7 (4.4)40.1 (6.6)2-c 40.2 (7.9)2-c 40.0 (4.6)2-c
Maximum velocity of the early ventricular filling (m.s−1)0.79 (0.15)0.68 (0.21)2-b 0.70 (0.13)2-a 0.65 (0.28)2-a
Maximum velocity of the late ventricular filling (m.s−1)0.51 (0.10)0.56 (0.17)2-a 0.61 (0.11)2-c 0.50 (0.22)2-d
E/A ratio2-150 1.58 (0.38)1.19 (0.44)2-c 1.17 (0.26)2-c 1.22 (0.61)2-a
Isovolumic relaxation time (s × 10−3)72.9 (12.9)103.0 (10.5)2-c 105.7 (8.0)2-c 99.5 (12.6)2-c
Heart rate (beats/min)72.1 (9.9)79.3 (13.4)2-a 76.7 (9.6)82.7 (16.8)2-a
Systolic blood pressure (mm Hg)122.0 (11.8)115.2 (10.4)2-a 118.4 (9.5)111.0 (10.2)2-c 2-e
Diastolic blood pressure (mm Hg)75.8 (8.1)69.3 (9.3)2-b 71.3 (10.2)66.5 (7.0)2-c

  • Values are mean (SD).

  • ↵2-150 E/A ratio: relation between peak velocity of early (E) and late (A) ventricular filling.

  • ↵2-a p<0.05 v healthy controls;

  • ↵2-b p<0.01 v healthy controls;

  • ↵2-c p<0.001 v healthy controls;

  • ↵2-d p<0.05 v well nourished HIV infected patients;

  • ↵2-e p<0.01 vwell nourished HIV infected patients.