Baseline characteristics of 13 patients with pulmonary hypertension
| Variables |
Adrenomedullin group (n=7) |
Placebo group (n=6) | p Value |
| Demographics | |||
| Age (years) | 52 (7) | 49 (8) | NS |
| Male/female | 2/5 | 4/2 | NS |
| NYHA functional class | |||
| II | 1 | 1 | NS |
| III | 5 | 4 | NS |
| IV | 1 | 1 | NS |
| Baseline haemodynamics | |||
| Heart rate (beats/min) | 73 (4) | 77 (4) | NS |
| mSAP (mm Hg) | 81 (3) | 82 (6) | NS |
| mPAP (mm Hg) | 62 (4) | 63 (7) | NS |
| CI (l/min) | 1.8 (0.2) | 1.9 (0.2) | NS |
| PVR (units) | 19.7 (1.4) | 19.9 (4.5) | NS |
| RAP (mm Hg) | 8 (1) | 7 (2) | NS |
| PCWP (mm Hg) | 8 (1) | 8 (1) | NS |
| Baseline blood gases | |||
| SaO2 (%) | 92 (3) | 93 (3) | NS |
| SvO2 (%) | 56 (5) | 59 (5) | NS |
Values are mean (SD) or n.
CI, cardiac index; HR, heart rate; mPAP, mean pulmonary arterial pressure; mSAP, mean systemic arterial pressure; NYHA, New York Heart Association; PCWP, pulmonary capillary wedge pressure; PVR, pulmonary vascular resistance; RAP, mean right atrial pressure; SaO2, arterial oxygen saturation; SvO2, mixed venous oxygen saturation.