Hormonal responses to infusion of adrenomedullin or placebo in patients with pulmonary hypertension
| Before | During | After | |
| Plasma noradrenaline (pg/ml) | |||
| Adrenomedullin group | 471 (240) | 618 (247) | 524 (260) |
| Placebo group | 528 (285) | 577 (317) | 585 (310) |
| Plasma adrenaline (pg/ml) | |||
| Adrenomedullin group | 74 (18) | 86 (14) | 79 (20) |
| Placebo group | 74 (28) | 75 (28) | 84 (30) |
| Plasma atrial natriuretic factor (pg/ml) | |||
| Adrenomedullin group | 156 (67) | 138 (51) | 141 (50) |
| Placebo group | 124 (64) | 131 (69) | 142 (81) |
| Plasma brain natriuretic peptide (pg/ml) | |||
| Adrenomedullin group | 236 (141) | 186 (107) | 196 (120) |
| Placebo group | 277 (208) | 280 (208) | 272 (191) |
| Plasma cGMP (pmol/ml) | |||
| Adrenomedullin group | 4.3 (0.8) | 3.6 (0.6) | 4.0 (0.8) |
| Placebo group | 3.9 (1.5) | 3.8 (1.6) | 4.0 (1.4) |
Values are mean (SD).
cGMP, cyclic guanosine 3′,5′-monophosphate.