Baseline characteristics of the different treatment groups
| All patients | SK with sc heparin | SK with iv heparin | tPA with iv heparin | SK + tPA with iv heparin | |
| Baseline variables | |||||
| Number of patients | 115 | 32 | 18 | 39 | 26 |
| Age (years) | 59 (1) | 61 (2) | 62 (2) | 58 (2) | 57 (2) |
| Female sex (%) | 19 | 19 | 39 | 21 | 4 |
| Infarct location (%) | |||||
| Anterior | 45 | 41 | 39 | 51 | 46 |
| Inferior | 49 | 50 | 61 | 46 | 46 |
| Other | 5 | 9 | 0 | 3 | 8 |
| Previous AMI (%) | 16 | 21 | 13 | 16 | 14 |
| Previous CABG (%) | 3 | 3 | 4 | 2 | 4 |
| Time to treatment (h) | 3.1 (0.1) | 2.9 (0.2) | 3.2 (0.3) | 3.2 (0.2) | 3.1 (0.3) |
| Time to angiography (h) | 1.6 (0.02) | 1.6 (0.02) | 1.6 (0.06) | 1.6 (0.03) | 1.6 (0.03) |
| Clinical events | |||||
| Stroke, all types (%) | 2 | 3 | 0 | 0 | 4 |
| Shock (%) | 2 | 0 | 4 | 2 | 4 |
| Angioplasty (%) | 9 | 18 | 17 | 4 | 0 |
| 30 day mortality (%) | 3 | 3 | 4 | 2 | 3 |
| TIMI score (number of patients) | |||||
| 0 | 23 | 14 | 4 | 4 | 1 |
| 1 | 6 | 2 | 4 | 0 | 0 |
| 2 | 36 | 11 | 4 | 12 | 9 |
| 3 | 50 | 5 | 6 | 23 | 16 |
| Infarct size calculated from HBDH (g eq/l) | 4.8 (0.3) | 5.3 (0.5) | 5.3 (1.0) | 4.3 (0.5) | 4.7 ( 0.8) |
Data are expressed as mean (SEM) or per cent unless specified.
AMI, acute myocardial infarction; CABG, coronary artery bypass graft; iv, intravenous; sc, subcutaneous; SK, streptokinase; TIMI, thrombolysis in myocardial infarction grade; t-PA, accelerated tissue plasminogen activator.